2005
Age related changes of baroreflex sensitivity in children and adolescents
ZÁVODNÁ, Eva, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Bohumil FIŠER, Nataša HONZÍKOVÁ et. al.Základní údaje
Originální název
Age related changes of baroreflex sensitivity in children and adolescents
Název česky
Na věku závislé změny baroreflexní citlivosti u dětí a dospívajících
Název anglicky
Age related changes of baroreflex sensitivity in children and adolescents
Autoři
ZÁVODNÁ, Eva (203 Česká republika, garant), Hana HRSTKOVÁ (203 Česká republika), Zuzana NOVÁKOVÁ (203 Česká republika), Bohumil FIŠER (203 Česká republika) a Nataša HONZÍKOVÁ (203 Česká republika)
Vydání
14th Meeting of Paediatric Research of Cenral European Countries, 2005
Další údaje
Jazyk
čeština
Typ výsledku
Konferenční abstrakt
Obor
30105 Physiology
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Kód RIV
RIV/00216224:14110/05:00013798
Organizační jednotka
Lékařská fakulta
Klíčová slova anglicky
baroreflex sensitivity; developemnt; children; adolescents
Štítky
Změněno: 1. 4. 2010 17:24, MUDr. Bc. Eva Závodná, Ph.D.
V originále
The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age.
Anglicky
The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age.
Návaznosti
| MSM0021622402, záměr |
| ||
| NR8006, projekt VaV |
|