2005
Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
LÁBROVÁ, Růžena, Nataša HONZÍKOVÁ, Eva MADĚROVÁ, Petra VYSOČANOVÁ, Zuzana NOVÁKOVÁ et. al.Základní údaje
Originální název
Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
Název česky
Věková závislost tloušťky intimy-medie, citlivosti baroreflexu a tepového intervalu u normotezních a hypertenzních osob.
Název anglicky
Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
Autoři
LÁBROVÁ, Růžena (203 Česká republika, garant), Nataša HONZÍKOVÁ (203 Česká republika), Eva MADĚROVÁ (203 Česká republika), Petra VYSOČANOVÁ (203 Česká republika), Zuzana NOVÁKOVÁ (203 Česká republika), Eva ZÁVODNÁ (203 Česká republika), Bohumil FIŠER (203 Česká republika) a Bořivoj SEMRÁD (203 Česká republika)
Vydání
Physiological Research, Praha, Academy of Sciences of the Czech Rep. 2005, 0862-8408
Další údaje
Jazyk
čeština
Typ výsledku
Článek v odborném periodiku
Obor
30105 Physiology
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 1.806
Kód RIV
RIV/00216224:14110/05:00014308
Organizační jednotka
Lékařská fakulta
UT WoS
000234481000004
Klíčová slova anglicky
Intima-media thickness; baroreflex sensitivity; hypertension; age; heart rate
Změněno: 18. 6. 2009 12:33, MUDr. Zuzana Nováková, Ph.D.
V originále
The interrelationship between baroreflex sensitivity expressed in ms/mmHg (BRS) or in Hz/mmHg (BRSf), carotid wall thickness (IMT), and age was investigated in 25 treated hypertensives and 23 normotensives with respect to the mean inter-beat interval (IBI) and blood pressure (BP). IMT was measured by ultrasonography. BRS and BRSf were determined by the spectral method (five-minute non-invasive beat-to-beat recording of BP and IBI, Finapres). Hypertensive patients have significantly increased IMT and decreased BRS and BRSf. The positive correlation between age and IMT and the negative correlation between age and BRS and BRSf are in agreement with the hypothesis that the age-dependent decrease of baroreflex sensitivity corresponds to the age-related structural changes of the carotid wall. Using two indices of baroreflex sensitivity, BRS and BRSf, we could show that baroreflex sensitivity in hypertensives is lower not only due to thickening of the carotid wall, but also due to aging.
Anglicky
The interrelationship between baroreflex sensitivity expressed in ms/mmHg (BRS) or in Hz/mmHg (BRSf), carotid wall thickness (IMT), and age was investigated in 25 treated hypertensives and 23 normotensives with respect to the mean inter-beat interval (IBI) and blood pressure (BP). IMT was measured by ultrasonography. BRS and BRSf were determined by the spectral method (five-minute non-invasive beat-to-beat recording of BP and IBI, Finapres). Hypertensive patients have significantly increased IMT and decreased BRS and BRSf. The positive correlation between age and IMT and the negative correlation between age and BRS and BRSf are in agreement with the hypothesis that the age-dependent decrease of baroreflex sensitivity corresponds to the age-related structural changes of the carotid wall. Using two indices of baroreflex sensitivity, BRS and BRSf, we could show that baroreflex sensitivity in hypertensives is lower not only due to thickening of the carotid wall, but also due to aging.
Návaznosti
| MSM0021622402, záměr |
| ||
| NA7362, projekt VaV |
|