JUŘICA, Jan. Cytochrom P450 a klinicky významné interakce (Cytochrome P450 and clinically important drug interactions). Rigorózní práce. Brno: VFU Brno, 2004, 98 pp.
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Basic information
Original name Cytochrom P450 a klinicky významné interakce
Name in Czech Cytochrom P450 a klinicky významné interakce
Name (in English) Cytochrome P450 and clinically important drug interactions
Authors JUŘICA, Jan.
Edition Rigorózní práce. Brno, 98 pp. 2004.
Publisher VFU Brno
Other information
Original language Czech
Type of outcome Book on a specialized topic
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English cytochrom P450; interaction; metabolism;
Tags cytochrom P450, interaction, metabolism
Tags Reviewed
Changed by Changed by: doc. PharmDr. Jan Juřica, Ph.D., učo 14537. Changed: 7/12/2006 10:22.
Abstract
V práci je vypracován přehled problematiky lidského cytochromu P450; jeho úlohy v metabolismu endogenních látek a léčiv, možností ovlivnění tohoto biotransformačního enzymu, možných interakcí a genetického polymorfismu.
Abstract (in English)
The problematics of cytochrome P450 as a main oxidative biotranformation way of xenobiotics as well as endogenous substrates is reviewed. Possible potentially dangerous interactions in drug biotransformation as well as polymoprhisms are maintained in the work.
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