DVOŘÁK, Petr, Dana DVOŘÁKOVÁ, Štefánia KOŠKOVÁ, Martina VODINSKÁ, M. NAJVIRTOVÁ, Daniel KREKÁČ and Aleš HAMPL. Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells. Stem Cells. 2005, vol. 23, No 8, p. 1200-1211. ISSN 1066-5099. |
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@article{611364, author = {Dvořák, Petr and Dvořáková, Dana and Košková, Štefánia and Vodinská, Martina and Najvirtová, M. and Krekáč, Daniel and Hampl, Aleš}, article_number = {8}, keywords = {stem cells}, language = {eng}, issn = {1066-5099}, journal = {Stem Cells}, title = {Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells}, volume = {23}, year = {2005} }
TY - JOUR ID - 611364 AU - Dvořák, Petr - Dvořáková, Dana - Košková, Štefánia - Vodinská, Martina - Najvirtová, M. - Krekáč, Daniel - Hampl, Aleš PY - 2005 TI - Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells JF - Stem Cells VL - 23 IS - 8 SP - 1200-1211 EP - 1200-1211 SN - 10665099 KW - stem cells N2 - Although the detection of several components of the fibroblast growth factor (FGF) signaling pathway in human embryonic stem cells (hESCs) has been reported, the functionality of that pathway and effects on cell fate decisions are yet to be established. In this study the expression of FGF-2, the prototypic member of the FGF family, and its receptors (FGFRs) was analyzed in undifferentiated and differentiating hESCs. The effects of FGF-2 on hESCs, acting as both exogenous and endogenous factor was also assessed. Based on the obtained data, we propose that endogenous FGF signaling pathway can be implicated in self-renewal and/or differentiation of hESCs. ER -
DVOŘÁK, Petr, Dana DVOŘÁKOVÁ, Štefánia KOŠKOVÁ, Martina VODINSKÁ, M. NAJVIRTOVÁ, Daniel KREKÁČ and Aleš HAMPL. Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells. \textit{Stem Cells}. 2005, vol.~23, No~8, p.~1200-1211. ISSN~1066-5099.
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