Toxic effects of cyanobacterial biomass in Japanese quail

PAŠKOVÁ, Veronika, Klára HILSCHEROVÁ, Pavel BABICA, Blanka SKOČOVSKÁ, Jana HORÁKOVÁ, Jií PIKULA and Blahoslav MARŠÁLEK. Toxic effects of cyanobacterial biomass in Japanese quail. In SETAC Europe 16th Annual Meeting, Abstract Book. 2006.

Basic information

• Original name: Toxic effects of cyanobacterial biomass in Japanese quail
• Name in Czech: Studie účinku biomasy sinic na křepelku japonskou
• Authors: PAŠKOVÁ, Veronika (203 Czech Republic, guarantor, belonging to the institution), Klára HILSCHEROVÁ (203 Czech Republic, belonging to the institution), Pavel BABICA (203 Czech Republic, belonging to the institution), Blanka SKOČOVSKÁ (203 Czech Republic), Jana HORÁKOVÁ (203 Czech Republic), Jií PIKULA (203 Czech Republic) and Blahoslav MARŠÁLEK (203 Czech Republic, belonging to the institution).
• Edition: SETAC Europe 16th Annual Meeting, Abstract Book, 2006.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 30304 Public and environmental health
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/06:00015344
• Organization unit: Faculty of Science
• Keywords in English: cyanobacteria; microcystin; bird; oxidative stress; detoxification; antioxidative system
• Tags: antioxidative system, bird, cyanobacteria, detoxification, microcystin, oxidative stress

Abstract

Cyanobacteria produce wide range of toxic compounds (cyanotoxins) which became important contaminants of aquatic ecosystems. Although several case studies implicated at least a contribution of toxic cyanobacterial blooms to the mass deaths of different bird species, there is a lack of toxicological experiments focused on avian toxicity of cyanobacteria or cyanotoxins. The aim of this study was to investigate the effects of cyanobacterial biomass using OECD 205: Avian dietary toxicity test with Japanese quail (Coturnix coturnix japonica). Animals were exposed to homogenized cyanobacterial bloom of Microcystis aeruginosa (containing the most prevalent cyanotoxins microcystins) in acute and (sub)chronic study. Effects on biochemical markers related to oxidative stress and detoxication were investigated in different tissues. Exposure to cyanobacterial biomass induced modulations of enzymatic and nonenzymatic antioxidants (including glutathione level and related enzymes) as well as lipid peroxidation.

Abstract (in Czech)

Sinice produkují široké spektrum látek, které ovlivňují vodní ekosystém. Tato studie se zabývala účinkem sinicových toxinů microcystinů na modulaci antioxidativních a detoxifikačních markerů u ptáků, konkrétně u křepelky japonské v akutní a chronické studii. Byly pozorovány významné účinky na biochemické úrovni a rovněž indukce oxidativního stresu.

Links

• AV0Z60050516, plan (intention): Name: Struktura, funkce a evoluce biodiversity fotoautotrofních organismů a hub: původ a příčiny jejich proměnlivosti, dynamika populací, společenstev a ekosystémů; využití vybraných výsledků k rozvoji Průhonického parku
• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)