VOKURKA, Jan, Pavla MORAVCOVÁ, Lucie KLAPUŠOVÁ, Martina KUKLETOVÁ and Lydie IZAKOVIČOVÁ HOLLÁ. The interaction of MMP-9 and IL-18 gene promoter polymorphisms in children with gingivitis. In Book of Abstracts, 5th Meeting of the European Mucosal Immunology Group. Prague, Czech Republic: European Mucosal Immunology Group, 2006, p. 167-167.
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Basic information
Original name The interaction of MMP-9 and IL-18 gene promoter polymorphisms in children with gingivitis
Name in Czech Interakce promotorových polymorfizmů v genech pro MMP-9 a IL-18 u dětí s gingivitidou
Authors VOKURKA, Jan, Pavla MORAVCOVÁ, Lucie KLAPUŠOVÁ, Martina KUKLETOVÁ and Lydie IZAKOVIČOVÁ HOLLÁ.
Edition Prague, Czech Republic, Book of Abstracts, 5th Meeting of the European Mucosal Immunology Group, p. 167-167, 1 pp. 2006.
Publisher European Mucosal Immunology Group
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English gene; polymorphism; IL-18; MMP-9; gingivitis
Tags gene, gingivitis, IL-18, MMP-9, polymorphism
Changed by Changed by: RNDr. JUDr. Vladimír Šmíd, CSc., učo 1084. Changed: 17/5/2007 17:55.
Abstract
Matrix metalloproteinase 9 (MMP-9) as a proteolytic enzyme plays an important role in tissue remodeling and repair. Interleukin 18 (IL-18) as a member of IL-1 proinflammatory family participates in regulation of expression of MMP-9. The aim of our study was to determine differences between Czech children with and without gingivitis in relation to the distribution of MMP-9 and IL-18 variants.
Abstract (in Czech)
Matrix metaloproteináza 9 (MMP-9) jako proteolytický enzym hraje důležitou úlohu v remodelaci tkání. Interleukin 18 (IL-18) se jako člen rodiny prozánětlivě působícího IL-1 podílí na regulaci exprese MMP-9. Cílem naší práce bylo porovnat rozdíly mezi českými dětmi s a bez gingivitidy ve vztahu k distribuci MMP-9 a IL-18 variant.
Links
NR8394, research and development projectName: Stav orálního zdraví u dětí sledovaných v programu ELSPAC Brno
Investor: Ministry of Health of the CR
NR9129, research and development projectName: Analýza polymorfizmů v genech prozánětlivých a remodelačních faktorů ve vztahu k imunitní reakci a klinickému stavu pacientů s parodontitidou
Investor: Ministry of Health of the CR
1M0528, research and development projectName: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre
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