2006
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a pilot study
PŘIKRYL, Radovan, Libor USTOHAL, Tomáš KAŠPÁREK, Hana KUČEROVÁ, Eva ČEŠKOVÁ et. al.Základní údaje
Originální název
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a pilot study
Název česky
Ovlivnění negativních příznaků schizofrenie pomocí rTMS: pilotní studie
Název anglicky
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a pilot study
Autoři
PŘIKRYL, Radovan (203 Česká republika, garant), Libor USTOHAL (203 Česká republika), Tomáš KAŠPÁREK (203 Česká republika), Hana KUČEROVÁ (203 Česká republika), Eva ČEŠKOVÁ (203 Česká republika) a Simona SKOTÁKOVÁ (203 Česká republika)
Vydání
European Neuropsychopharmacology, Amsterdam (The Netherlands), Elsevier, 2006, 0924-977X
Další údaje
Jazyk
čeština
Typ výsledku
Článek v odborném periodiku
Obor
30000 3. Medical and Health Sciences
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 3.794
Kód RIV
RIV/00216224:14110/06:00017487
Organizační jednotka
Lékařská fakulta
UT WoS
000240771301241
Klíčová slova anglicky
negative symptoms; schizophrenia; rTMS; treatment
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 19. 6. 2009 14:34, prof. MUDr. Eva Češková, CSc.
V originále
In patients treated with real rTMS before treatment the score of total PANSS was 58.2, positive PANSS 7.7, negative PANSS 21.3 and general PANSS 29.2 and after treatment the score of total PANSS was 45.2, positive PANSS 7.5, negative PANSS 15.5 and general PANSS 22.2. Except of positive PANSS all other PANSS subscales decreased statistically significantly (p<0.05, Wilcoxon Matched Pairs Test). In patients treated with sham rTMS before treatment the score of total PANSS was 64.2, positive PANSS 8.9, negative PANSS 22.1 and general PANSS 33.2 and after treatment the score of total PANSS was 57.0, positive PANSS 8.3, negative PANSS 20.6 and general PANSS 28.1. General and total PANSS subscales decreased only statistically significantly (p<0.05, Wilcoxon Matched Pairs Test), there was no change in negative PANSS. High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of negative symptoms and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
Anglicky
In patients treated with real rTMS before treatment the score of total PANSS was 58.2, positive PANSS 7.7, negative PANSS 21.3 and general PANSS 29.2 and after treatment the score of total PANSS was 45.2, positive PANSS 7.5, negative PANSS 15.5 and general PANSS 22.2. Except of positive PANSS all other PANSS subscales decreased statistically significantly (p<0.05, Wilcoxon Matched Pairs Test). In patients treated with sham rTMS before treatment the score of total PANSS was 64.2, positive PANSS 8.9, negative PANSS 22.1 and general PANSS 33.2 and after treatment the score of total PANSS was 57.0, positive PANSS 8.3, negative PANSS 20.6 and general PANSS 28.1. General and total PANSS subscales decreased only statistically significantly (p<0.05, Wilcoxon Matched Pairs Test), there was no change in negative PANSS. High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of negative symptoms and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
Návaznosti
| MSM0021622404, záměr |
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| NR7986, projekt VaV |
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