2006
Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus
KOBETIČOVÁ, Klára, Jakub HOFMAN a Ivan HOLOUBEKZákladní údaje
Originální název
Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus
Název česky
Efekty PAHs a jejich N-heterocyklických analogů na roupici Enchytraeus crypticus
Autoři
KOBETIČOVÁ, Klára (203 Česká republika), Jakub HOFMAN (203 Česká republika, garant) a Ivan HOLOUBEK (203 Česká republika)
Vydání
Abstract Book of SETAC Europe the 16th Annual Meeting, 2006
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
10511 Environmental sciences
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Kód RIV
RIV/00216224:14310/06:00016309
Organizační jednotka
Přírodovědecká fakulta
Klíčová slova anglicky
ecotoxicology; azaPAHs; soil
Štítky
Příznaky
Mezinárodní význam
Změněno: 24. 2. 2010 22:31, prof. RNDr. Jakub Hofman, Ph.D.
V originále
Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both by individual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 525/04/P159
Česky
Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both by individual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 525/04/P159
Návaznosti
| GP525/04/P159, projekt VaV |
| ||
| MSM0021622412, záměr |
|