Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus

KOBETIČOVÁ, Klára, Jakub HOFMAN and Ivan HOLOUBEK. Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus. In Abstract Book of SETAC Europe the 16th Annual Meeting. 2006.

Basic information

• Original name: Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus
• Name in Czech: Efekty PAHs a jejich N-heterocyklických analogů na roupici Enchytraeus crypticus
• Authors: KOBETIČOVÁ, Klára (203 Czech Republic), Jakub HOFMAN (203 Czech Republic, guarantor) and Ivan HOLOUBEK (203 Czech Republic).
• Edition: Abstract Book of SETAC Europe the 16th Annual Meeting, 2006.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 10511 Environmental sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/06:00016309
• Organization unit: Faculty of Science
• Keywords in English: ecotoxicology; azaPAHs; soil
• Tags: azaPAHs, ecotoxicology, soil
• Tags: International impact

Abstract

Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both by individual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 525/04/P159

Abstract (in Czech)

Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both by individual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 525/04/P159

Links

• GP525/04/P159, research and development project: Name: Vliv nově rozpoznávaných prioritních perzistentních organických polutantů (POPs) na organismy v půdním ekosystému

Investor: Czech Science Foundation, Effects of newly recognized priority persistent organic pollutants (POPs) on organisms of soil ecosystem

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)