The long-lasting improvement of sexual dysfunction in patients
with advanced, fluctuating Parkinson's disease induced by
pergolide: Results of an open, prospective, six months and
one-year follow-up

J 2005

The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: Results of an open, prospective, six months and one-year follow-up

POHANKA, Michal, Petr KAŇOVSKÝ, Martin BAREŠ, Jiří PULKRÁBEK, Ivan REKTOR et. al.

Základní údaje

Originální název

The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: Results of an open, prospective, six months and one-year follow-up

Název česky

Dlouhodobé zlepšení sexuální dysfunkce podáváním pergolidu u pacientů v pokročilém stadiu Parkinsovony nemoci- prospektivní 6 měsíční sledování

Autoři

POHANKA, Michal (203 Česká republika), Petr KAŇOVSKÝ (203 Česká republika, garant), Martin BAREŠ (203 Česká republika), Jiří PULKRÁBEK (203 Česká republika) a Ivan REKTOR (203 Česká republika)

Vydání

Česká a slovenská neurologie a neurochirurgie, Česká lékařská společnost J.E.Purkyně, 2005, 1210-7859

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.070

Kód RIV

RIV/00216224:14110/05:00031906

Organizační jednotka

Lékařská fakulta

UT WoS

000233791000006

Klíčová slova anglicky

Pergolid; Parkinson disease; treatment; sexual dysfunction

Štítky

Parkinson disease, pergolid, sexual dysfunction, treatment

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 3. 2010 23:31, prof. MUDr. Martin Bareš, Ph.D.

Anotace

ORIG CZ

V originále

The presented study aimed to assess whether the latter effect of pergolide in advanced Parkinson's disease remains stable also in the longer time period. Fourteen male patients suffering from Parkinson's disease, each of whom had been treated with L-DOPA, and in whom additional treatment with peroral dopaminergic agonist (DA) was needed, were followed for a six-months and twelve-months period. Pergolide mesylate (Permax (R)) was given to each patient, and titrated to a total daily dose of 3 mg. All of the patients were taking L-DOPA. There were statistically significant differences between the values of UPDRS III motor subscale, UPDRS IV (complications of therapy) subscale and all subscales of IIEF when months 0 and 1 were compared with the results obtained at months 3, 6 and 12. Pergolide mesylate, when added to L-DOPA, significantly improved sexual functions in younger male patients who were still interested in sexual activities in all aspects.

Česky

Dlouhodobé zlepšení sexuální dysfunkce podáváním pergolidu u pacientů v pokročilém stadiu Parkinsovony nemoci- prospektivní 6 měsíční sledování

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

POHANKA, Michal, Petr KAŇOVSKÝ, Martin BAREŠ, Jiří PULKRÁBEK a Ivan REKTOR. The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: Results of an open, prospective, six months and one-year follow-up. Česká a slovenská neurologie a neurochirurgie. Česká lékařská společnost J.E.Purkyně, 2005, roč. 68, č. 3, s. 164-168. ISSN 1210-7859.

@article{711904,
   author = {Pohanka, Michal and Kaňovský, Petr and Bareš, Martin and Pulkrábek, Jiří and Rektor, Ivan},
   article_number = {3},
   keywords = {Pergolid; Parkinson disease; treatment; sexual dysfunction},
   language = {eng},
   issn = {1210-7859},
   journal = {Česká a slovenská neurologie a neurochirurgie},
   title = {The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: Results of an open, prospective, six months and one-year follow-up},
   volume = {68},
   year = {2005}
}

TY  - JOUR
ID  - 711904
AU  - Pohanka, Michal - Kaňovský, Petr - Bareš, Martin - Pulkrábek, Jiří - Rektor, Ivan
PY  - 2005
TI  - The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: Results of an open, prospective, six months and one-year follow-up
JF  - Česká a slovenská neurologie a neurochirurgie
VL  - 68
IS  - 3
SP  - 164-168
EP  - 164-168
PB  - Česká lékařská společnost J.E.Purkyně
SN  - 12107859
KW  - Pergolid
KW  - Parkinson disease
KW  - treatment
KW  - sexual dysfunction
N2  - The presented study aimed to assess whether the latter effect of pergolide in advanced Parkinson's disease remains stable also in the longer time period. Fourteen male patients suffering from Parkinson's disease, each of whom had been treated with L-DOPA, and in whom additional treatment with peroral dopaminergic agonist (DA) was needed, were followed for a six-months and twelve-months period. Pergolide mesylate (Permax (R)) was given to each patient, and titrated to a total daily dose of 3 mg. All of the patients were taking L-DOPA. There were statistically significant differences between the values of UPDRS III motor subscale, UPDRS IV (complications of therapy) subscale and all subscales of IIEF when months 0 and 1 were compared with the results obtained at months 3, 6 and 12. Pergolide mesylate, when added to L-DOPA, significantly improved sexual functions in younger male patients who were still interested in sexual activities in all aspects.
ER  -

POHANKA, Michal, Petr KAŇOVSKÝ, Martin BAREŠ, Jiří PULKRÁBEK a Ivan REKTOR. The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: Results of an open, prospective, six months and one-year follow-up. \textit{Česká a slovenská neurologie a neurochirurgie}. Česká lékařská společnost J.E.Purkyně, 2005, roč.~68, č.~3, s.~164-168. ISSN~1210-7859.

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