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@inproceedings{716008,
author = {Tomandl, Josef and Salzman, Richard and Horáková, Zuzana and Kostřica, Rom},
address = {Bratislava},
booktitle = {Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.},
edition = {1.},
keywords = {head and neck cell carcinoma; oxidative stress; cell-mediated immunity},
language = {eng},
location = {Bratislava},
isbn = {978-80-969663-2-5},
pages = {52-52},
publisher = {Mind and Health, civil association},
title = {Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma},
year = {2007}
}
TY - JOUR
ID - 716008
AU - Tomandl, Josef - Salzman, Richard - Horáková, Zuzana - Kostřica, Rom
PY - 2007
TI - Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma
PB - Mind and Health, civil association
CY - Bratislava
SN - 9788096966325
KW - head and neck cell carcinoma
KW - oxidative stress
KW - cell-mediated immunity
N2 - Oxidative stress, alterations in host immunity and inflammation may contribute to genesis and progression of head and neck squamous cell carcinoma (HNSCC). We investigated relationships between malondialdehyde (MDA) as a marker of lipid peroxidation and parameters of activated macrophages, i.e. tumor necrosis factor alpha as a marker of inflammation and neopterin as a marker of cell-mediated immunity and clinical stage of HNSCC. Our results confirm the role of activated macrophages and the cellular immune system in HNSCC. In patients with activated T-lymphocytes, levels of TNF alpha inversely reflected the prognosis of disease. Although production of MDA in HNSCC patients is normal, it seems that activated T-lymphocytes contribute to lipid peroxidation.
ER -
TOMANDL, Josef, Richard SALZMAN, Zuzana HORÁKOVÁ a Rom KOSTŘICA. Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma. In \textit{Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.}. 1. vyd. Bratislava: Mind and Health, civil association, 2007, s.~52-52. ISBN~978-80-969663-2-5.
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