JANA, Suchomelová and Eva TÁBORSKÁ. Evaluation of benzophenanthridine alkaloids content in the selected species of family Papaveraceae. In Chemistry, Pharmacology and Biosynthesis of Alkaloids. Turecko, Antalya: Chemistry, Pharmacology and Biosynthesis of Alkaloids, 2006, p. 89.
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Basic information
Original name Evaluation of benzophenanthridine alkaloids content in the selected species of family Papaveraceae
Name in Czech Zhodnocení obsahu benzofenanthridinových alkaloidů ve vybraných druzích čeledi Papaveraceae
Authors JANA, Suchomelová and Eva TÁBORSKÁ.
Edition Turecko, Antalya, Chemistry, Pharmacology and Biosynthesis of Alkaloids, p. 89-89, 2006.
Publisher Chemistry, Pharmacology and Biosynthesis of Alkaloids
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 40100 4.1 Agriculture, Forestry, and Fisheries
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English Benzophenanthridine alkaloids; Papaveraceae; HPLC
Tags Benzophenanthridine Alkaloids, HPLC, Papaveraceae
Tags International impact
Changed by Changed by: Mgr. Jana Gregorová, Ph.D., učo 152400. Changed: 10/9/2007 14:02.
Abstract
Using HPLC method we analyzed the content (as the weight % of dry root) of alkaloids in the root extracts of selected species of family Papaveraceae. Reversed column MAX RP C 12 Phenomenex Synergi was used, mobile phase consisted of heptansulfonic acid with triethanolamine in redistilled water, pH 2,5.Acetonitrile gradient 25 60% during 30 minutes.The highest content of sanguinarine and chelerythrine was found in root of Dicranostigma lactucoides. The rare minor alkaloids chelirubine, chelilutine and macarpine were detected in Macleaya microcarpa and Stylophorum lasiocarpum. The presence of sanguirubine was approved only in Sanguinaria canadensis.
Abstract (in Czech)
S použitím metody HPLC jsme stanovily obsah alkaloidů v kořenových extraktech vybraných druhů z čeledi Papaveraceae. Jako stacionární fázi byla použita reverzní kolona MAX RP Phenomenex Synergi, mobilní fáze byla tvořena z heptansulfonové kyseliny a triethanolaminu v redestilované vodě. Největší obsah sanguinarinu a chelerythrinu byl nalezen v kořeni D. lactucoides. Minoritní alkaloidy chelirubin, chelilutin a macarpin byly stanoveny v M. microcarpa a S. lasiocarpum. Přítomnost sanguirubinu byla potrvzena pouze v S. canadensis.
Links
GA525/04/0017, research and development projectName: Rostlinné zdroje benzofenanthridinových alkaloidů a účinek těchto alkaloidů na normální a nádorové buňky
Investor: Czech Science Foundation, Plant sources of benzophenanthridine alkaloids and effects of these alkaloid on normal and cancer cells
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