PAZDERA, Pavel and Walid Fathalla MOHAMED. Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates. ARKIVOC. Florida: ARKAT-USA, 2007, vol. 2007, i, p. 236-243. ISSN 1424-6376.
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Basic information
Original name Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates
Name in Czech Syntéza a reakce methyl-2-[3-(2-fenylchinazolin-4-yl)thioureido]alkanoátů
Authors PAZDERA, Pavel (203 Czech Republic, guarantor) and Walid Fathalla MOHAMED (818 Egypt).
Edition ARKIVOC, Florida, ARKAT-USA, 2007, 1424-6376.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10401 Organic chemistry
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.253
RIV identification code RIV/00216224:14310/07:00020278
Organization unit Faculty of Science
UT WoS 000248918000025
Keywords in English Non-nucleoside RT inhibitors; quinazoline; thioureas; amino acids; imidoyl isothiocyanate; Domino-reaction; intramolecular cyclization
Tags amino acids, DOMINO-REACTION, imidoyl isothiocyanate, intramolecular cyclization, Non-nucleoside RT inhibitors, quinazoline, thioureas
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Pavel Pazdera, CSc., učo 2276. Changed: 23/11/2007 07:54.
Abstract
Methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates bearing an amino acid ester residue were prepared by a novel three step sequential reaction of N-(2-cyanophenyl)benzimidoyl isothioyanate with amino acid methyl ester hydrochlorides. Some chemoselective reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates with alkyl halides were studied.
Abstract (in Czech)
Methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates bearing an amino acid ester residue were prepared by a novel three step sequential reaction of N-(2-cyanophenyl)benzimidoyl isothioyanate with amino acid methyl ester hydrochlorides. Some chemoselective reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates with alkyl halides were studied.
Links
GA203/01/1333, research and development projectName: Chalkogenorganické sloučeniny - příprava, transformace a strukturní studie
Investor: Czech Science Foundation, Chalcogen organic compounds - synthesis, transformation and structure elucidation
MSM 143100011, plan (intention)Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů
Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles
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