Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates
PAZDERA, Pavel and Walid Fathalla MOHAMED. Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates. ARKIVOC. Florida: ARKAT-USA, 2007, vol. 2007, i, p. 236-243. ISSN 1424-6376. |
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Original name | Synthesis and reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates |
Name in Czech | Syntéza a reakce methyl-2-[3-(2-fenylchinazolin-4-yl)thioureido]alkanoátů |
Authors | PAZDERA, Pavel (203 Czech Republic, guarantor) and Walid Fathalla MOHAMED (818 Egypt). |
Edition | ARKIVOC, Florida, ARKAT-USA, 2007, 1424-6376. |
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Original language | English |
Type of outcome | Article in a journal |
Field of Study | 10401 Organic chemistry |
Country of publisher | United States of America |
Confidentiality degree | is not subject to a state or trade secret |
Impact factor | Impact factor: 1.253 |
RIV identification code | RIV/00216224:14310/07:00020278 |
Organization unit | Faculty of Science |
UT WoS | 000248918000025 |
Keywords in English | Non-nucleoside RT inhibitors; quinazoline; thioureas; amino acids; imidoyl isothiocyanate; Domino-reaction; intramolecular cyclization |
Tags | amino acids, DOMINO-REACTION, imidoyl isothiocyanate, intramolecular cyclization, Non-nucleoside RT inhibitors, quinazoline, thioureas |
Tags | International impact, Reviewed |
Changed by | Changed by: doc. RNDr. Pavel Pazdera, CSc., učo 2276. Changed: 23/11/2007 07:54. |
Abstract |
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Methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates bearing an amino acid ester residue were prepared by a novel three step sequential reaction of N-(2-cyanophenyl)benzimidoyl isothioyanate with amino acid methyl ester hydrochlorides. Some chemoselective reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates with alkyl halides were studied. |
Abstract (in Czech) |
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Methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates bearing an amino acid ester residue were prepared by a novel three step sequential reaction of N-(2-cyanophenyl)benzimidoyl isothioyanate with amino acid methyl ester hydrochlorides. Some chemoselective reactions of methyl 2-[3-(2-phenylquinazolin-4-yl)thioureido]alkanoates with alkyl halides were studied. |
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GA203/01/1333, research and development project | Name: Chalkogenorganické sloučeniny - příprava, transformace a strukturní studie |
Investor: Czech Science Foundation, Chalcogen organic compounds - synthesis, transformation and structure elucidation | |
MSM 143100011, plan (intention) | Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů |
Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles |
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