ŠULCOVÁ, Alexandra and Jana PISTOVČÁKOVÁ. Role of cannabinoid CB1 receptor inhibition in regulation of anxiety and depression related behaviours in mice. In Programme and Abstracts, 9th International Neuroscience Winter Conference. Soledne, Austria: Medical University Innsbruck, 2007, p. 66.
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Basic information
Original name Role of cannabinoid CB1 receptor inhibition in regulation of anxiety and depression related behaviours in mice
Name in Czech Úloha inhibice kanabinoidních receptorů CB1 v regulaci chování myší hodnocenému jako anxiosní a depresivní
Authors ŠULCOVÁ, Alexandra and Jana PISTOVČÁKOVÁ.
Edition Soledne, Austria, Programme and Abstracts, 9th International Neuroscience Winter Conference, p. 66-66, 2007.
Publisher Medical University Innsbruck
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English CB1 receptor antagonists; anxiety; depression; mice
Tags anxiety, CB1 receptor antagonists, Depression, mice
Tags International impact
Changed by Changed by: prof. MUDr. Alexandra Šulcová, CSc., učo 1937. Changed: 4/6/2007 15:16.
Abstract
Two CB1 receptor antagonists rimonabant and AM251 showed just tendency to increase aggressive activities mice, without any other significant behavioural changes in the timid mice, that means no anxiolytic effects. However, our findings confirmed that rimonabant may have a suggested beneficial effect on depression and social stress-related behaviour.
Abstract (in Czech)
Dva antagonisti CB1 kanabinoidního receptoru rimonabant a AM 251 vykázaly pouze tendenci ke zvýšení agresivity agresivních myší a žádné změny chování u myší plachých, tzn. žádný anxiolytický efekt. Avšak rimonabant měnil chování myší ve smyslu antidepresivního a protistresového účinku.
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