2007
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a case study
PŘIKRYL, Radovan, Simona SKOTÁKOVÁ, Tomáš KAŠPÁREK, Eva ČEŠKOVÁ, Hana KUČEROVÁ et. al.Základní údaje
Originální název
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a case study
Název česky
Ovlivnění negativních příznaků schizofrenie prostřednictvím repetitivní transkraniální magnetické stimulace: kazuistické sdělení
Název anglicky
Influencing negative symptoms of schizophrenia with repetitive transcranial magnetic stimulation: a case study
Autoři
PŘIKRYL, Radovan (203 Česká republika, garant), Simona SKOTÁKOVÁ (203 Česká republika), Tomáš KAŠPÁREK (203 Česká republika), Eva ČEŠKOVÁ (203 Česká republika), Hana KUČEROVÁ (203 Česká republika) a Libor USTOHAL (203 Česká republika)
Vydání
Acta Neuropsychiatrica, Australia, Blackwell Publishing, 2007, 0924-2708
Další údaje
Jazyk
čeština
Typ výsledku
Článek v odborném periodiku
Obor
30000 3. Medical and Health Sciences
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 1.206
Kód RIV
RIV/00216224:14110/07:00019061
Organizační jednotka
Lékařská fakulta
UT WoS
000245231200008
Klíčová slova anglicky
negative symptoms; schizophrenia; rTMS
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 19. 6. 2009 14:02, prof. MUDr. Eva Češková, CSc.
V originále
Background: The present trial was designed to investigate the influence of repetitive transcranial magnetic stimulation (rTMS) on negative schizophrenic symptoms using high frequency stimulation of the left dorsolateral prefrontal cortex in a simple blind randomised design. Methods: The study was carried out on a 42-year-old schizophrenic patient (paranoid subtype) with prominent negative symptoms who was firstly treated with sham rTMS during the first three weeks and then with real high frequency during the following three weeks. He was rated before and after the sham and after the real rTMS therapy for positive, negative and depressive symptoms. Results: rTMS was superior to sham treatment in reduction of negative and depressive symptoms. Conclusion: High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of severity of negative symptoms in a patient with chronic schizophrenia and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
Anglicky
Background: The present trial was designed to investigate the influence of repetitive transcranial magnetic stimulation (rTMS) on negative schizophrenic symptoms using high frequency stimulation of the left dorsolateral prefrontal cortex in a simple blind randomised design. Methods: The study was carried out on a 42-year-old schizophrenic patient (paranoid subtype) with prominent negative symptoms who was firstly treated with sham rTMS during the first three weeks and then with real high frequency during the following three weeks. He was rated before and after the sham and after the real rTMS therapy for positive, negative and depressive symptoms. Results: rTMS was superior to sham treatment in reduction of negative and depressive symptoms. Conclusion: High frequency rTMS applied over the left dorsolateral prefrontal cortex led to a reduction of severity of negative symptoms in a patient with chronic schizophrenia and may be beneficial as an augmentation option to antipsychotics in the treatment of negative symptoms of schizophrenia.
Návaznosti
| MSM0021622404, záměr |
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| NR7986, projekt VaV |
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