Další formáty:
BibTeX
LaTeX
RIS
@article{720330,
author = {Skočovská, Blanka and Hilscherová, Klára and Babica, Pavel and Adamovský, Ondřej and Banďouchová, Hana and Horáková, Jana and Knotková, Zdenka and Maršálek, Blahoslav and Pašková, Veronika and Pikula, Jiří},
article_number = {1},
keywords = {Cyanobacterial water bloom; Avian toxicity tests; Peroral exposure; Biochemistry; Histopathology; Electron microscopy;},
language = {eng},
issn = {0041-0101},
journal = {Toxicon},
title = {Effects of cyanobacterial biomass on the Japanese quail},
volume = {49},
year = {2007}
}
TY - JOUR
ID - 720330
AU - Skočovská, Blanka - Hilscherová, Klára - Babica, Pavel - Adamovský, Ondřej - Banďouchová, Hana - Horáková, Jana - Knotková, Zdenka - Maršálek, Blahoslav - Pašková, Veronika - Pikula, Jiří
PY - 2007
TI - Effects of cyanobacterial biomass on the Japanese quail
JF - Toxicon
VL - 49
IS - 1
SP - 493-803
EP - 493-803
SN - 00410101
KW - Cyanobacterial water bloom
KW - Avian toxicity tests
KW - Peroral exposure
KW - Biochemistry
KW - Histopathology
KW - Electron microscopy;
N2 - Mortality of wild aquatic birds has recently been attributed to cyanobacterial toxins. Despite this, no experimental studies on the effects of defined doses of microcystins administered orally to birds exist. In this experiment, four groups of male Japanese quails daily ingesting 10 ml of Microcystis biomass containing 0.045, 0.459, 4.605 or 46.044 mg of microcystins, respectively, for 10 and 30 days, showed no mortality. Histopathological hepatic changes in birds after the biomass exposure included cloudy swelling of hepatocytes, vacuolar dystrophy, steatosis and hyperplasia of lymphatic centres. On subcellular level, shrunken nuclei of hepatocytes containing ring-like nucleoli, cristolysis within mitochondria and vacuoles with pseudomyelin structures were present. Vacuolar degeneration of the testicular germinative epithelium was found in two exposed males. Statistically significant differences in biochemical parameters were on day 10 of exposure only. They comprised increased activities of lactate dehydrogenase and a drop in blood glucose in birds receiving the highest dose of the biomass. Principal component analysis revealed a pattern of responses in biochemical parameters on day 10 that clearly separated the two greatest exposure groups from the controls and lower exposures. The results indicate that diagnosis of microcystin intoxication solely based on clinical biochemical and haematological parameters is hardly possible in birds.
ER -
SKOČOVSKÁ, Blanka, Klára HILSCHEROVÁ, Pavel BABICA, Ondřej ADAMOVSKÝ, Hana BANĎOUCHOVÁ, Jana HORÁKOVÁ, Zdenka KNOTKOVÁ, Blahoslav MARŠÁLEK, Veronika PAŠKOVÁ a Jiří PIKULA. Effects of cyanobacterial biomass on the Japanese quail. \textit{Toxicon}. 2007, roč.~49, č.~1, s.~493-803, 804 s. ISSN~0041-0101.
|
