Comparative TOF-SIMS and MALDI TOF-MS analysis on different
chromatographic planar substrates

J 2007

Comparative TOF-SIMS and MALDI TOF-MS analysis on different chromatographic planar substrates

TALIAN, Ivan, Andrej ORIŇÁK, Jan PREISLER, Andreas HEILE, Lucia ONOFREJOVÁ et. al.

Základní údaje

Originální název

Comparative TOF-SIMS and MALDI TOF-MS analysis on different chromatographic planar substrates

Název česky

TOF-SIMS a MALDI TOF-MS analýza na různých chromatografických tenkých vrstvách

Autoři

TALIAN, Ivan (703 Slovensko), Andrej ORIŇÁK (703 Slovensko), Jan PREISLER (203 Česká republika, garant, domácí), Andreas HEILE (276 Německo), Lucia ONOFREJOVÁ (203 Česká republika, domácí), Dušan KANIANSKÝ (703 Slovensko) a Heinrich ARLINGHAUS (276 Německo)

Vydání

Journal of Separation Science, Weinheim, WILEY-VCH Verlag GmbH & Co. 2007, 1615-9306

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10406 Analytical chemistry

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.632

Kód RIV

RIV/00216224:14310/07:00022372

Organizační jednotka

Přírodovědecká fakulta

UT WoS

000250986700002

Klíčová slova anglicky

TLC-MS; TOF-SIMS; MALDI TOF-MS; Fragmentation; Chromatographic substrates

Štítky

Chromatographic substrates, Fragmentation, MALDI TOF-MS, TLC-MS, TOF-SIMS

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 7. 2017 15:27, prof. Mgr. Jan Preisler, Ph.D.

Anotace

ORIG CZ

V originále

A comparison is made between two high resolution, surface-based, mass spectrometric methods: time-of-flight secondary ion mass spectrometry (TOF-SIMS) and matrix-assisted laser desorption/ionisation mass spectrometry (MALDI TOF-MS) in indication of abietic and gibberellic acids molecular profiles on different chromatographic thin layers. The analytes were applied to silica gel chromatographic thin layers with SIMS on-line interfacing channel, monolithic silica gel ultra-thin layers, and thin layers specifically designed for direct Raman spectroscopic analysis. Two MALDI matrices were used in this research: ferulic acid and 2,5-dihydroxybenzoic acid. The silica gel SIMS-interfacing channel strongly supported formation of numerous different MALDI MS fragments with abietic and gibberellic acids, and ferulic acid matrix. The most intense fragments belonged to [M-OH]+ and [M]+ ions from ferulic acid. Intense conjugates were detected with gibberellic acid. The MALDI MS spectrum from the monolithic silica gel surface showed very low analyte signal intensity and it was not possible to obtain MALDI spectra from a Raman spectroscopy treated chromatographic layer. The MALDI TOF MS gibberellic acid fragmentation profile was shielded by the matrix used and was accompanied by poor analyte identification. The most useful TOF-SIMS analytical signal response was obtained from analytes separated on monolithic silica gel and a SIMS-interfacing modified silica gel surface. New horizons with nanostructured surfaces call for high resolution MS methods (which cannot readily be miniaturised like many optical and electrochemical methods) to be integrated in chip and nanoscale detection systems.

Česky

Srovnání TOF-SIMS a MALDI TOF-MS profilů biologicky významných organických kyselin na různých chromatografických tenkých vrstvách.

Návaznosti

MSM0021622415, záměr

Název: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Molekulární podstata buněčných a tkáňových regulací

Citovat

TALIAN, Ivan, Andrej ORIŇÁK, Jan PREISLER, Andreas HEILE, Lucia ONOFREJOVÁ, Dušan KANIANSKÝ a Heinrich ARLINGHAUS. Comparative TOF-SIMS and MALDI TOF-MS analysis on different chromatographic planar substrates. Journal of Separation Science. Weinheim: WILEY-VCH Verlag GmbH & Co., 2007, roč. 30, č. 16, s. 2570 - 2582. ISSN 1615-9306.

@article{721048,
   author = {Talian, Ivan and Oriňák, Andrej and Preisler, Jan and Heile, Andreas and Onofrejová, Lucia and Kanianský, Dušan and Arlinghaus, Heinrich},
   article_location = {Weinheim},
   article_number = {16},
   keywords = {TLC-MS; TOF-SIMS; MALDI TOF-MS; Fragmentation; Chromatographic substrates},
   language = {eng},
   issn = {1615-9306},
   journal = {Journal of Separation Science},
   title = {Comparative TOF-SIMS and MALDI TOF-MS analysis on different chromatographic planar substrates},
   volume = {30},
   year = {2007}
}

TY  - JOUR
ID  - 721048
AU  - Talian, Ivan - Oriňák, Andrej - Preisler, Jan - Heile, Andreas - Onofrejová, Lucia - Kanianský, Dušan - Arlinghaus, Heinrich
PY  - 2007
TI  - Comparative TOF-SIMS and MALDI TOF-MS analysis on different chromatographic planar substrates
JF  - Journal of Separation Science
VL  - 30
IS  - 16
SP  - 2570 - 2582
EP  - 2570 - 2582
PB  - WILEY-VCH Verlag GmbH & Co.
SN  - 16159306
KW  - TLC-MS
KW  - TOF-SIMS
KW  - MALDI TOF-MS
KW  - Fragmentation
KW  - Chromatographic substrates
N2  - A comparison is made between two high resolution, surface-based, mass spectrometric methods: time-of-flight secondary ion mass spectrometry (TOF-SIMS) and matrix-assisted laser desorption/ionisation mass spectrometry (MALDI TOF-MS) in indication of abietic and gibberellic acids molecular profiles on different chromatographic thin layers. The analytes were applied to silica gel chromatographic thin layers with SIMS on-line interfacing channel, monolithic silica gel ultra-thin layers, and thin layers specifically designed for direct Raman spectroscopic analysis. Two MALDI matrices were used in this research: ferulic acid and 2,5-dihydroxybenzoic acid. The silica gel SIMS-interfacing channel strongly supported formation of numerous different MALDI MS fragments with abietic and gibberellic acids, and ferulic acid matrix. The most intense fragments belonged to [M-OH]+ and [M]+ ions from ferulic acid. Intense conjugates were detected with gibberellic acid. The MALDI MS spectrum from the monolithic silica gel surface showed very low analyte signal intensity and it was not possible to obtain MALDI spectra from a Raman spectroscopy treated chromatographic layer. The MALDI TOF MS gibberellic acid fragmentation profile was shielded by the matrix used and was accompanied by poor analyte identification. The most useful TOF-SIMS analytical signal response was obtained from analytes separated on monolithic silica gel and a SIMS-interfacing modified silica gel surface. New horizons with nanostructured surfaces call for high resolution MS methods (which cannot readily be miniaturised like many optical and electrochemical methods) to be integrated in chip and nanoscale detection systems.
ER  -

TALIAN, Ivan, Andrej ORIŇÁK, Jan PREISLER, Andreas HEILE, Lucia ONOFREJOVÁ, Dušan KANIANSKÝ a Heinrich ARLINGHAUS. Comparative TOF-SIMS and MALDI TOF-MS analysis on different chromatographic planar substrates. \textit{Journal of Separation Science}. Weinheim: WILEY-VCH Verlag GmbH \&{} Co., 2007, roč.~30, č.~16, s.~2570 - 2582. ISSN~1615-9306.

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