J 2007

Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal

BRABEC, Kamil a Vojtěch MORNSTEIN

Základní údaje

Originální název

Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal

Název česky

Detekce ultrazvukové kavitace založená na nízkofrekvenční analýze akustického signálu

Autoři

BRABEC, Kamil (203 Česká republika, garant) a Vojtěch MORNSTEIN (203 Česká republika)

Vydání

Central European Journal of Biology, Springer Versita, 2007, 1895-104X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10610 Biophysics

Stát vydavatele

Polsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.250

Kód RIV

RIV/00216224:14110/07:00032317

Organizační jednotka

Lékařská fakulta

UT WoS

000246984400005

Klíčová slova anglicky

ultrasound; ultrasonic cavitation; echocontrast agent; microbubbles; low-frequency analysis; cavitation threshold
Změněno: 15. 3. 2010 20:25, prof. RNDr. Vojtěch Mornstein, CSc.

Anotace

V originále

The acoustic cavitation phenomenon constitutes a potential hazard in ultrasound diagnostics and therapy so that early and effective detection of cavitation is of great interest. However, cavitation might even bring a higher risk especially when an echocontrast agent based on microbubbles is used. The major goal of the present work was to develop a cavitation detection method based on increased level of cavitation noise in the range of low frequencies ( about 1 Hz). This method was applied in vitro using a model of body fluid containing a model echocontrast agent, such as 5% solution of lyophilized egg albumin, which was sonicated by ultrasound disintegrator. Ultrasound signal evokes cavitation in microbubble suspension accompanied by a certain level of cavitation acoustic noise. The level of noise voltage increased in the frequency range of 0.1 to 2 Hz in the presence of cavitation. Hence, this method makes it possible to determine the value of cavitation threshold. In addition, we examined how the cavitation threshold is affected by temperature and viscosity. It was found that the cavitation threshold decreased with growing temperature while it increased with growing viscosity.