JONES, Sarah, Margaret FLORENCE, Ian ELLIS, Kateřina KAŇKOVÁ, Seth SCHOR and Ana SCHOR. Co-Expression by Keratinocytes of Migration Stimulating Factor (MSF) and a Functional Inhibitor of its Bioactivity (MSFI). Experimental Cell Research. Elsevier, 2007, vol. 313, No 20, p. 4145-4157. ISSN 0014-4827. |
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@article{725659, author = {Jones, Sarah and Florence, Margaret and Ellis, Ian and Kaňková, Kateřina and Schor, Seth and Schor, Ana}, article_number = {20}, keywords = {MSF; NGAL; lipocalin; keratinocytes; fibroblasts; HaCat}, language = {eng}, issn = {0014-4827}, journal = {Experimental Cell Research}, title = {Co-Expression by Keratinocytes of Migration Stimulating Factor (MSF) and a Functional Inhibitor of its Bioactivity (MSFI)}, volume = {313}, year = {2007} }
TY - JOUR ID - 725659 AU - Jones, Sarah - Florence, Margaret - Ellis, Ian - Kaňková, Kateřina - Schor, Seth - Schor, Ana PY - 2007 TI - Co-Expression by Keratinocytes of Migration Stimulating Factor (MSF) and a Functional Inhibitor of its Bioactivity (MSFI) JF - Experimental Cell Research VL - 313 IS - 20 SP - 4145-4157 EP - 4145-4157 PB - Elsevier SN - 00144827 KW - MSF KW - NGAL KW - lipocalin KW - keratinocytes KW - fibroblasts KW - HaCat N2 - Data presented in this communication indicate that MSF is constitutively expressed by keratinocytes in culture, but is rendered functionally inactive by the co-secretion of an inhibitor (MSFI). This inhibitor was identified as NGAL. MSFI activity was found in NGAL obtained from four different sources: keratinocytes, neutrophils and recombinant protein isolated from both procaryotic and eucaryotic sources. This is a novel activity of NGAL which does not seem to be mediated by previously reported mechanisms, such as iron transport or direct protein-protein binding. ER -
JONES, Sarah, Margaret FLORENCE, Ian ELLIS, Kateřina KAŇKOVÁ, Seth SCHOR and Ana SCHOR. Co-Expression by Keratinocytes of Migration Stimulating Factor (MSF) and a Functional Inhibitor of its Bioactivity (MSFI). \textit{Experimental Cell Research}. Elsevier, 2007, vol.~313, No~20, p.~4145-4157. ISSN~0014-4827.
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