Markov model in the evaluation of breast cancer screening program in the Czech Republic

BUREŠOVÁ, Lucie and Eva GELNAROVÁ. Markov model in the evaluation of breast cancer screening program in the Czech Republic. In TIES 2007. Brno, Czech Republic: TIES, 2007, p. 42. ISBN 978-80-210-4333-6.

Basic information

• Original name: Markov model in the evaluation of breast cancer screening program in the Czech Republic
• Name in Czech: Markovský model v hodnocení screeningového programu karcinomu prsu v České republice
• Authors: BUREŠOVÁ, Lucie and Eva GELNAROVÁ.
• Edition: Brno, Czech Republic, TIES 2007, p. 42-42, 2007.
• Publisher: TIES

Other information

• Original language: English
• Type of outcome: Proceedings paper
• Field of Study: 30200 3.2 Clinical medicine
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• Organization unit: Faculty of Medicine
• ISBN: 978-80-210-4333-6
• Keywords in English: breast cancer; screening; Markov model; mean sojourn time; sensitivity; interval cancers
• Tags: breast cancer, interval cancers, Markov Model, mean sojourn time, screening, sensitivity

Abstract

Breast cancer is the most common women cancer and the second most common cause of death from cancer in industrially developed countries. It has been shown with randomised trials that screening by mammography reduces by 30% mortality from breast cancer for women aged 50 years or more. In the Czech Republic, national-wide mammographic screening programme for breast cancer has started in September 2002. Generally, it is desirable to estimate the effect of screening such as the sensitivity of screening test and the average length of the preclinical detectable period (mean sojourn time) to assess the ability of screening to affect subsequent mortality. Aim of this work is to make a pilot study of the affect of screening in the Czech Republic. The study is based on the data collected with MaSc - Czech national information system for data management of National Program of Screening of Breast Cancer. The three-state Markov model has been used with states: no disease - preclinical, screen detectable disease - clinical phase. Opposite to standard practices, the knowledge of interval cases (cancers diagnosed between screens) for different age groups is not required. Number of interval cases is, unfortunately, unknown in the Czech Republic, due to the existence of screening units and diagnostic centres separately.

Abstract (in Czech)

Markovský model v hodnocení screeningového programu karcinomu prsu v České republice