VETTERL, Vladimír, Jiří VANĚK, Lukáš FOJT, Stanislav HASOŇ, Sonia BARTÁKOVÁ and Raimo SILVENNOINEN. Adsorption of oligonucleotides on titanium surface. In BES 2007 Toulouse, Book of Abstracts. 2007.
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Basic information
Original name Adsorption of oligonucleotides on titanium surface.
Name in Czech Adsorpce oligonukleotidů na povrchu titanu.
Authors VETTERL, Vladimír, Jiří VANĚK, Lukáš FOJT, Stanislav HASOŇ, Sonia BARTÁKOVÁ and Raimo SILVENNOINEN.
Edition BES 2007 Toulouse, Book of Abstracts, 2007.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10610 Biophysics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English Adsorption; oligonucleotides; titanium;
Tags adsorption, Oligonucleotides, titanium
Tags International impact, Reviewed
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 21/2/2020 13:31.
Abstract
Titanium is frequently used as a biomaterial for hard tissue replacement, such as dental and orthopaedic implants. The surface morphology influence the final interactions of the implant with the surrounding environment. Recently, we have investigated the application of diffractive optical element (DOE), which is a computer-generated hologram fabricated using advanced electron beam lithography techniques, for sensing a diversity of material properties. Electrochemical impedance spectroscopy (EIS), voltammetry, AFM, and DOE was used for the investigations of adsorption of oligonucleotides on the titanium surface and the effect of mechanical (polished, etched and/or gritted surface) and chemical modification of titanium surface was studied. From the EIS, voltammetric and optical measurements the conclusions of the effect of solvent and physical or chemical modification of titanium surface on the purine (AAG)12 and pyrimidine (TTC)12 oligonucleotide adsorption was delivered.
Abstract (in Czech)
Titan se často používá jako biomateriál pro náhradu tvrdých tkání, jako jsou zubní a ortopedické implantáty. Morfologie povrchu implantátu ovlivňuje jeho výslednou interakci s okolím. Nedávno jsme ke studiu povrchových vlastností materiálů použili difrakční optický element (DOE). Elektrochemická impedanční spektroskopie (EIS), voltametrie, AGFM a DOE jsme použili ke studiu adsorpce oligonukleotidů na povrch titanu. Sledovali jsme vliv mechanické (leštění, leptání a pískování) a chemické úpravy povrchu titanu na adsorpci oligonukleotidů (AAG)12 a (TTC)12.
Links
1M0528, research and development projectName: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre
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