| RŮŽIČKA, Filip, Veronika HOLÁ, Miroslav VOTAVA and Renata TEJKALOVÁ. Importance of biofilm in Candida parapsilosis and evaluation of its susceptibility to antifungal agents by colorimetric method. Folia Microbiologica. Praha: Institute of Microbiology of AV ČR, 2007, vol. 52, No 3, p. 209-214, 214 pp. ISSN 0015-5632. |
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@article{749669,
author = {Růžička, Filip and Holá, Veronika and Votava, Miroslav and Tejkalová, Renata},
article_location = {Praha},
article_number = {3},
keywords = {Biofilm; Candida parapsilosis; susceptibility; antifungal agents; colorimetric method},
language = {eng},
issn = {0015-5632},
journal = {Folia Microbiologica},
title = {Importance of biofilm in Candida parapsilosis and evaluation of its susceptibility to antifungal agents by colorimetric method},
volume = {52},
year = {2007}
}
TY - JOUR
ID - 749669
AU - Růžička, Filip - Holá, Veronika - Votava, Miroslav - Tejkalová, Renata
PY - 2007
TI - Importance of biofilm in Candida parapsilosis and evaluation of its susceptibility to antifungal agents by colorimetric method
JF - Folia Microbiologica
VL - 52
IS - 3
SP - 209-214
EP - 209-214
PB - Institute of Microbiology of AV ČR
SN - 00155632
KW - Biofilm
KW - Candida parapsilosis
KW - susceptibility
KW - antifungal agents
KW - colorimetric method
N2 - The ability of C. parapsilosis, an important cause of nosocomial infections, to produce biofilm was evaluated in 32 bloodstream isolates and 85 strains isolated from skin. The biofilm formation was found in 19 (59.4 %) blood isolates and only in 33 (38.8 %) isolates from skin. The antifungal susceptibility was assessed for amphotericin B, itraconazole and voriconazole in planktonic and biofilm form of the 19 biofilm-positive bloodstream strains by broth microdilution method according to NCCLS standards. The method was modified by the use of resazurin as a colorimetric indicator of the metabolically active cells which makes the determination of the effect of antifungal agents easier. Biofilm form of all tested strains were more resistant than their planktonic form.
ER -
RŮŽIČKA, Filip, Veronika HOLÁ, Miroslav VOTAVA and Renata TEJKALOVÁ. Importance of biofilm in Candida parapsilosis and evaluation of its susceptibility to antifungal agents by colorimetric method. \textit{Folia Microbiologica}. Praha: Institute of Microbiology of AV ČR, 2007, vol.~52, No~3, p.~209-214, 214 pp. ISSN~0015-5632.
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