Early Recanalization Rates and Clinical Outcomes in Patients
With Tandem Internal Carotid Artery/Middle Cerebral Artery
Occlusion and Isolated Middle Cerebral Artery Occlusion

J 2005

Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion

KIM, Jo Sik, Garami ZSOLT, Robert MIKULÍK, Carlos MOLINA, Andrei ALEXANDROV et. al.

Základní údaje

Originální název

Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion

Název česky

Četnost časné rekanalizace a klinický stav u pacientů se tandemovou okluzí arteria karotis interna/arteria cerebri media a izolovanou okluzí arteria cerebri media

Autoři

KIM, Jo Sik (410 Korejská republika), Garami ZSOLT (348 Maďarsko), Robert MIKULÍK (203 Česká republika, garant), Carlos MOLINA (724 Španělsko) a Andrei ALEXANDROV (840 Spojené státy)

Vydání

Stroke : a journal of cerebral circulation, Dallas, American Heart Association, 2005, 0039-2499

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 5.855

Organizační jednotka

Lékařská fakulta

UT WoS

000227523800148

Klíčová slova anglicky

stroke acute; outcome; ultrasonography; Doppler transcranial; thrombolysis

Štítky

Doppler transcranial, outcome, stroke acute, thrombolysis, Ultrasonography

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 18. 6. 2009 13:48, prof. MUDr. Robert Mikulík, Ph.D.

Anotace

ORIG CZ

V originále

Background: Patients with isolated middle cerebral artery (MCA) and tandem MCA/internal carotid artery (ICA)obstruction have similar presenting symptoms and stroke severity. We aimed to investigate early recanalization of MCA and clinical outcomes in patients with tandem ICA/MCA obstructions and isolated MCA occlusion. Methods: Patients with MCA occlusion on pretreatment transcranial Doppler were treated with intravenous tissue plasminogen activator. ICA lesions were detected with carotid duplex. Early neurological improvement (ENI) was defined by reduction of National Institutes of Health Stroke Scale (NIHSS) 10 or more points or total NIHSS 3 or less points. Good outcome at 3 months was a modified Rankin score of 2 or more. Results: Among 104 patients, 31% had tandem lesions and 69% had isolated MCA occlusions. Complete recanalization rate was 39% in isolated MCA occlusion group and 9% in tandem group (P=0.002). ENI at 24 hours occurred in 46% of the isolated MCA occlusion group and in 25% of the tandem group (P=0.045). Good outcome was achieved by 30% and 39% respective patients (NS). Conclusion: The tandem lesion group showed lower early recanalization rate and ENI rate than the isolated MCA occlusion group. Despite this, good outcomes were similar in both groups.

Česky

Četnost časné rekanalizace a klinický stav u pacientů se tandemovou okluzí arteria karotis interna/arteria cerebri media byly horsi nez s izolovanou okluzí arteria cerebri media

Citovat

KIM, Jo Sik, Garami ZSOLT, Robert MIKULÍK, Carlos MOLINA a Andrei ALEXANDROV. Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion. Stroke : a journal of cerebral circulation. Dallas: American Heart Association, 2005, roč. 36, č. 4, s. 869-871. ISSN 0039-2499.

@article{768458,
   author = {Kim, Jo Sik and Zsolt, Garami and Mikulík, Robert and Molina, Carlos and Alexandrov, Andrei},
   article_location = {Dallas},
   article_number = {4},
   keywords = {stroke acute; outcome; ultrasonography; Doppler transcranial; thrombolysis},
   language = {eng},
   issn = {0039-2499},
   journal = {Stroke : a journal of cerebral circulation},
   title = {Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion},
   volume = {36},
   year = {2005}
}

TY  - JOUR
ID  - 768458
AU  - Kim, Jo Sik - Zsolt, Garami - Mikulík, Robert - Molina, Carlos - Alexandrov, Andrei
PY  - 2005
TI  - Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion
JF  - Stroke : a journal of cerebral circulation
VL  - 36
IS  - 4
SP  - 869-871
EP  - 869-871
PB  - American Heart Association
SN  - 00392499
KW  - stroke acute
KW  - outcome
KW  - ultrasonography
KW  - Doppler transcranial
KW  - thrombolysis
N2  - Background: Patients with isolated middle cerebral artery (MCA) and tandem MCA/internal carotid artery (ICA)obstruction have similar presenting symptoms and stroke severity. We aimed to investigate early recanalization of MCA and clinical outcomes in patients with tandem ICA/MCA obstructions and isolated MCA occlusion. Methods: Patients with MCA occlusion on pretreatment transcranial Doppler were treated with intravenous tissue plasminogen activator. ICA lesions were detected with carotid duplex. Early neurological improvement (ENI) was defined by reduction of National Institutes of Health Stroke Scale (NIHSS) 10 or more points or total NIHSS 3 or less points. Good outcome at 3 months was a modified Rankin score of 2 or more. Results: Among 104 patients, 31% had tandem lesions and 69% had isolated MCA occlusions. Complete recanalization rate was 39% in isolated MCA occlusion group and 9% in tandem group (P=0.002). ENI at 24 hours occurred in 46% of the isolated MCA occlusion group and in 25% of the tandem group (P=0.045). Good outcome was achieved by 30% and 39% respective patients (NS). Conclusion: The tandem lesion group showed lower early recanalization rate and ENI rate than the isolated MCA occlusion group. Despite this, good outcomes were similar in both groups.
ER  -

KIM, Jo Sik, Garami ZSOLT, Robert MIKULÍK, Carlos MOLINA a Andrei ALEXANDROV. Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion. \textit{Stroke : a journal of cerebral circulation}. Dallas: American Heart Association, 2005, roč.~36, č.~4, s.~869-871. ISSN~0039-2499.

Podrobný výpis o publikaci