| KIM, Jo Sik, Garami ZSOLT, Robert MIKULÍK, Carlos MOLINA a Andrei ALEXANDROV. Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion. Stroke : a journal of cerebral circulation. Dallas: American Heart Association, 2005, roč. 36, č. 4, s. 869-871. ISSN 0039-2499. |
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@article{768458,
author = {Kim, Jo Sik and Zsolt, Garami and Mikulík, Robert and Molina, Carlos and Alexandrov, Andrei},
article_location = {Dallas},
article_number = {4},
keywords = {stroke acute; outcome; ultrasonography; Doppler transcranial; thrombolysis},
language = {eng},
issn = {0039-2499},
journal = {Stroke : a journal of cerebral circulation},
title = {Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion},
volume = {36},
year = {2005}
}
TY - JOUR
ID - 768458
AU - Kim, Jo Sik - Zsolt, Garami - Mikulík, Robert - Molina, Carlos - Alexandrov, Andrei
PY - 2005
TI - Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion
JF - Stroke : a journal of cerebral circulation
VL - 36
IS - 4
SP - 869-871
EP - 869-871
PB - American Heart Association
SN - 00392499
KW - stroke acute
KW - outcome
KW - ultrasonography
KW - Doppler transcranial
KW - thrombolysis
N2 - Background: Patients with isolated middle cerebral artery (MCA) and tandem MCA/internal carotid artery (ICA)obstruction have similar presenting symptoms and stroke severity. We aimed to investigate early recanalization of MCA and clinical outcomes in patients with tandem ICA/MCA obstructions and isolated MCA occlusion. Methods: Patients with MCA occlusion on pretreatment transcranial Doppler were treated with intravenous tissue plasminogen activator. ICA lesions were detected with carotid duplex. Early neurological improvement (ENI) was defined by reduction of National Institutes of Health Stroke Scale (NIHSS) 10 or more points or total NIHSS 3 or less points. Good outcome at 3 months was a modified Rankin score of 2 or more. Results: Among 104 patients, 31% had tandem lesions and 69% had isolated MCA occlusions. Complete recanalization rate was 39% in isolated MCA occlusion group and 9% in tandem group (P=0.002). ENI at 24 hours occurred in 46% of the isolated MCA occlusion group and in 25% of the tandem group (P=0.045). Good outcome was achieved by 30% and 39% respective patients (NS). Conclusion: The tandem lesion group showed lower early recanalization rate and ENI rate than the isolated MCA occlusion group. Despite this, good outcomes were similar in both groups.
ER -
KIM, Jo Sik, Garami ZSOLT, Robert MIKULÍK, Carlos MOLINA a Andrei ALEXANDROV. Early Recanalization Rates and Clinical Outcomes in Patients With Tandem Internal Carotid Artery/Middle Cerebral Artery Occlusion and Isolated Middle Cerebral Artery Occlusion. \textit{Stroke : a journal of cerebral circulation}. Dallas: American Heart Association, 2005, roč.~36, č.~4, s.~869-871. ISSN~0039-2499.
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