J 2008

Cryptosporidia: epicellular parasites embraced by the host cell membrane.

VALIGUROVÁ, Andrea, Miloslav JIRKŮ, Břetislav KOUDELA, Milan GELNAR, David MODRÝ et. al.

Basic information

Original name

Cryptosporidia: epicellular parasites embraced by the host cell membrane.

Name in Czech

Cryptosporidia: epicellular parasites embraced by the host cell membrane.

Authors

VALIGUROVÁ, Andrea (703 Slovakia, guarantor), Miloslav JIRKŮ (203 Czech Republic), Břetislav KOUDELA (203 Czech Republic), Milan GELNAR (203 Czech Republic), David MODRÝ (203 Czech Republic) and Jan ŠLAPETA (36 Australia)

Edition

International Journal for Parasitology, Australia, Elsevier Science Ltd. 2008, 0020-7519

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Australia

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.752

RIV identification code

RIV/00216224:14310/08:00026291

Organization unit

Faculty of Science

UT WoS

000257001300004

Keywords in English

Cryptosporidium; host cell invasion; epicellular; parasitophorous sac; ultrastructure

Tags

International impact, Reviewed

Abstract

V originále

The ultrastructure of 2 gastric cryptosporidia, C. muris from experimentally infected rodents (Mastomys natalensis) and Cryptosporidium sp. toad from naturally infected toads (Duttaphrynus melanostictus), was studied using electron microscopy. Observations allowed us to map ultrastructural aspects of the cryptosporidian invasion process and the origin of a parasitophorous sac. Invading parasites attach to the host cell, followed by gradual envelopment, with the host cell membrane folds eventually forming the parasitophorous sac. Cryptosporidian developmental stages remain epicellular during the entire life cycle. The parasite development is illustrated in detail using high resolution field emission scanning electron microscopy. This provides a new insight into the ultrastructural detail of host-parasite interactions and species specific differences manifested in frequency of detachment of the parasitophorous sac, radial folds of the parasitophorous sac and stem-formation of the parasitised host cell.

In Czech

The ultrastructure of 2 gastric cryptosporidia, C. muris from experimentally infected rodents (Mastomys natalensis) and Cryptosporidium sp. toad from naturally infected toads (Duttaphrynus melanostictus), was studied using electron microscopy. Observations allowed us to map ultrastructural aspects of the cryptosporidian invasion process and the origin of a parasitophorous sac. Invading parasites attach to the host cell, followed by gradual envelopment, with the host cell membrane folds eventually forming the parasitophorous sac. Cryptosporidian developmental stages remain epicellular during the entire life cycle. The parasite development is illustrated in detail using high resolution field emission scanning electron microscopy. This provides a new insight into the ultrastructural detail of host-parasite interactions and species specific differences manifested in frequency of detachment of the parasitophorous sac, radial folds of the parasitophorous sac and stem-formation of the parasitised host cell.

Links

MSM0021622416, plan (intention)
Name: Diverzita biotických společenstev a populací: kauzální analýza variability v prostoru a čase
Investor: Ministry of Education, Youth and Sports of the CR, Diversity of Biotic Communities and Populations: Causal Analysis of variation in space and time