Cryptosporidia: epicellular parasites embraced by the host cell membrane.

VALIGUROVÁ, Andrea, Miloslav JIRKŮ, Břetislav KOUDELA, Milan GELNAR, David MODRÝ and Jan ŠLAPETA. Cryptosporidia: epicellular parasites embraced by the host cell membrane. International Journal for Parasitology. Australia: Elsevier Science Ltd., 2008, vol. 38, xx, p. 913 - 922. ISSN 0020-7519.

Basic information

• Original name: Cryptosporidia: epicellular parasites embraced by the host cell membrane.
• Name in Czech: Cryptosporidia: epicellular parasites embraced by the host cell membrane.
• Authors: VALIGUROVÁ, Andrea (703 Slovakia, guarantor), Miloslav JIRKŮ (203 Czech Republic), Břetislav KOUDELA (203 Czech Republic), Milan GELNAR (203 Czech Republic), David MODRÝ (203 Czech Republic) and Jan ŠLAPETA (36 Australia).
• Edition: International Journal for Parasitology, Australia, Elsevier Science Ltd. 2008, 0020-7519.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 10600 1.6 Biological sciences
• Country of publisher: Australia
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 3.752
• RIV identification code: RIV/00216224:14310/08:00026291
• Organization unit: Faculty of Science
• UT WoS: 000257001300004
• Keywords in English: Cryptosporidium; host cell invasion; epicellular; parasitophorous sac; ultrastructure
• Tags: Cryptosporidium, epicellular, host cell invasion, parasitophorous sac, ultrastructure
• Tags: International impact, Reviewed

Abstract

The ultrastructure of 2 gastric cryptosporidia, C. muris from experimentally infected rodents (Mastomys natalensis) and Cryptosporidium sp. toad from naturally infected toads (Duttaphrynus melanostictus), was studied using electron microscopy. Observations allowed us to map ultrastructural aspects of the cryptosporidian invasion process and the origin of a parasitophorous sac. Invading parasites attach to the host cell, followed by gradual envelopment, with the host cell membrane folds eventually forming the parasitophorous sac. Cryptosporidian developmental stages remain epicellular during the entire life cycle. The parasite development is illustrated in detail using high resolution field emission scanning electron microscopy. This provides a new insight into the ultrastructural detail of host-parasite interactions and species specific differences manifested in frequency of detachment of the parasitophorous sac, radial folds of the parasitophorous sac and stem-formation of the parasitised host cell.

Abstract (in Czech)

The ultrastructure of 2 gastric cryptosporidia, C. muris from experimentally infected rodents (Mastomys natalensis) and Cryptosporidium sp. toad from naturally infected toads (Duttaphrynus melanostictus), was studied using electron microscopy. Observations allowed us to map ultrastructural aspects of the cryptosporidian invasion process and the origin of a parasitophorous sac. Invading parasites attach to the host cell, followed by gradual envelopment, with the host cell membrane folds eventually forming the parasitophorous sac. Cryptosporidian developmental stages remain epicellular during the entire life cycle. The parasite development is illustrated in detail using high resolution field emission scanning electron microscopy. This provides a new insight into the ultrastructural detail of host-parasite interactions and species specific differences manifested in frequency of detachment of the parasitophorous sac, radial folds of the parasitophorous sac and stem-formation of the parasitised host cell.

Links

• MSM0021622416, plan (intention): Name: Diverzita biotických společenstev a populací: kauzální analýza variability v prostoru a čase

Investor: Ministry of Education, Youth and Sports of the CR, Diversity of Biotic Communities and Populations: Causal Analysis of variation in space and time