| SVÍŽENSKÁ, Ivana, Petr DUBOVÝ a Alexandra ŠULCOVÁ. Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures. A short review. Pharmacology Biochemistry and Behavior. Elsevier, 2008, roč. 90, č. 4, s. 501-511, 12 s. ISSN 0091-3057. |
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@article{775842,
author = {Svíženská, Ivana and Dubový, Petr and Šulcová, Alexandra},
article_number = {4},
keywords = {Cannabinoid; CB receptors; Endocannabinoid system; Nervous system; Therapeutic potential},
language = {eng},
issn = {0091-3057},
journal = {Pharmacology Biochemistry and Behavior},
title = {Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures. A short review},
volume = {90},
year = {2008}
}
TY - JOUR
ID - 775842
AU - Svíženská, Ivana - Dubový, Petr - Šulcová, Alexandra
PY - 2008
TI - Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures. A short review
JF - Pharmacology Biochemistry and Behavior
VL - 90
IS - 4
SP - 501-511
EP - 501-511
PB - Elsevier
SN - 00913057
KW - Cannabinoid
KW - CB receptors
KW - Endocannabinoid system
KW - Nervous system
KW - Therapeutic potential
N2 - In the last 25 years data has grown exponentially dealing with the discovery of the endocannabinoid system consisting of specific cannabinoid receptors, their endogenous ligands, and enzymatic systems of their biosynthesis and degradation. Progress is being made in the development of novel agonists and antagonists with receptor subtype selectivity which should help in providing a greater understanding of the physiological role of the endocannabinoid system and perhaps also in a broad number of pathologies. This could lead to advances with important therapeutic potential of drugs modulating activity of endocannabinoid system. The aim of this review is to highlight distribution of the CB1 and CB2 receptor subtypes in the nervous system and functional involvement of their specific ligands.
ER -
SVÍŽENSKÁ, Ivana, Petr DUBOVÝ a Alexandra ŠULCOVÁ. Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures. A short review. \textit{Pharmacology Biochemistry and Behavior}. Elsevier, 2008, roč.~90, č.~4, s.~501-511, 12 s. ISSN~0091-3057.
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