2008
Eugregarines and cryptosporidia: peculiar parasites with epicellular development
VALIGUROVÁ, Andrea a Břetislav KOUDELAZákladní údaje
Originální název
Eugregarines and cryptosporidia: peculiar parasites with epicellular development
Název česky
Eugregarines and cryptosporidia: peculiar parasites with epicellular development
Autoři
VALIGUROVÁ, Andrea (703 Slovensko, garant, domácí) a Břetislav KOUDELA (203 Česká republika)
Vydání
Xth European Multicolloquium of Parasitology, Program and Abstract book, 2008
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
10600 1.6 Biological sciences
Stát vydavatele
Francie
Utajení
není předmětem státního či obchodního tajemství
Kód RIV
RIV/00216224:14310/08:00026545
Organizační jednotka
Přírodovědecká fakulta
Klíčová slova anglicky
gregarine; cryptosporidium; epicellular; parasitic protist
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 18. 3. 2011 16:57, doc. RNDr. Andrea Bardůnek Valigurová, Ph.D.
V originále
Gregarines and cryptosporidia are often considered to be peculiar apicomplexans, as they exhibit unique features in their attachment strategy, and some phylogenetic analyses have pointed out their affinity. This study focuses on the ultrastructural analysis of their early development and host-parasite interactions, and searches for explicit characteristics common to both apicomplexans. The formation of attachment site was studied in two eugregarines, Gregarina polymorpha and G. steini from laboratory reared insects, and obtained data were directly compared with comparable features observed during attachment process of Cryptosporidium muris in the stomach of experimentally infected rodents. In both apicomplexans, the apical complexes disappear early during cell invasion and parasites are attached to the host cell by their apical processes, i.e. epimerite in eugregarines and the feeder organelle in cryptosporidia. Data presented herein support the term epicellular to reflect cryptosporidian localization, rather than the term intracellular-extracytoplasmic traditionally used throughout the literature. The cryptosporidian attachment strategy is very similar to that of the eugregarines, which are also epicellularly located on the microvillous surface of host epithelial cells, although not enveloped by host cell membrane folds. Despite a few differences found among the studied eugregarines and cryptosporidia, our data support their close relationship.
Česky
Gregarines and cryptosporidia are often considered to be peculiar apicomplexans, as they exhibit unique features in their attachment strategy, and some phylogenetic analyses have pointed out their affinity. This study focuses on the ultrastructural analysis of their early development and host-parasite interactions, and searches for explicit characteristics common to both apicomplexans. The formation of attachment site was studied in two eugregarines, Gregarina polymorpha and G. steini from laboratory reared insects, and obtained data were directly compared with comparable features observed during attachment process of Cryptosporidium muris in the stomach of experimentally infected rodents. In both apicomplexans, the apical complexes disappear early during cell invasion and parasites are attached to the host cell by their apical processes, i.e. epimerite in eugregarines and the feeder organelle in cryptosporidia. Data presented herein support the term epicellular to reflect cryptosporidian localization, rather than the term intracellular-extracytoplasmic traditionally used throughout the literature. The cryptosporidian attachment strategy is very similar to that of the eugregarines, which are also epicellularly located on the microvillous surface of host epithelial cells, although not enveloped by host cell membrane folds. Despite a few differences found among the studied eugregarines and cryptosporidia, our data support their close relationship.
Návaznosti
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