BOB, Petr, PF FREYBERGH, D. JAŠOVÁ, M. ŠUSTA, J. PAVLAT, T. ZIMA, H. BENAKOVÁ, G. BIZIK, Miroslav SVĚTLÁK, J. VEVERA, J. MIKLOŠKO, K. HÁJEK and J. RABOCH. Depression, cortisol and somatoform dissociative symtoms. NEUROENDOCRINOLOGY LETTERS. Sweden: Neuro Endocrinology Letters ISSN 0172–780X, 2008, 29/2008, 2/2008, p. 235-239. ISSN 0172-780X.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Depression, cortisol and somatoform dissociative symtoms
Name in Czech Deprese, kortizol a somatoformní disociativní symptomy
Authors BOB, Petr (203 Czech Republic, guarantor), PF FREYBERGH (703 Slovakia), D. JAŠOVÁ (203 Czech Republic), M. ŠUSTA (203 Czech Republic), J. PAVLAT (203 Czech Republic), T. ZIMA (203 Czech Republic), H. BENAKOVÁ (203 Czech Republic), G. BIZIK (203 Czech Republic), Miroslav SVĚTLÁK (203 Czech Republic), J. VEVERA (203 Czech Republic), J. MIKLOŠKO (203 Czech Republic), K. HÁJEK (203 Czech Republic) and J. RABOCH (203 Czech Republic).
Edition NEUROENDOCRINOLOGY LETTERS, Sweden, Neuro Endocrinology Letters ISSN 0172–780X, 2008, 0172-780X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.359
RIV identification code RIV/00216224:14110/08:00026888
Organization unit Faculty of Medicine
UT WoS 000255490000007
Keywords in English Depression cortisol and somatoform dissociative symtoms
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Petr Bob, Ph.D., učo 45604. Changed: 19/6/2009 11:27.
Abstract
OBJECTIVE: According to recent findings neuroendocrine response related to dissociative symptoms is related to dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis but HPA axis functioning as related to dissociation is only partially understood. METHOD: With the aim to test the relationship between basal serum cortisol and dissociative symptoms measured as somatoform and psychic dissociation we performed clinical testing and biochemical analysis in 30 inpatients with diagnosis of unipolar depression (mean age 41.46, SD=13.68). RESULTS: The results show that cortisol as an index of HPA axis functioning manifests significant relationship to somatoform dissociative symptoms (r=-0.40; p=0.014). CONCLUSIONS: The result indicates relationship between HPA-axis reactivity and somatoform dissociative symptoms in unipolar depressive patients and suggests that somatoform dissociation presents a defense mechanism related to a passive coping response.
Abstract (in Czech)
OBJECTIVE: According to recent findings neuroendocrine response related to dissociative symptoms is related to dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis but HPA axis functioning as related to dissociation is only partially understood. METHOD: With the aim to test the relationship between basal serum cortisol and dissociative symptoms measured as somatoform and psychic dissociation we performed clinical testing and biochemical analysis in 30 inpatients with diagnosis of unipolar depression (mean age 41.46, SD=13.68). RESULTS: The results show that cortisol as an index of HPA axis functioning manifests significant relationship to somatoform dissociative symptoms (r=-0.40; p=0.014). CONCLUSIONS: The result indicates relationship between HPA-axis reactivity and somatoform dissociative symptoms in unipolar depressive patients and suggests that somatoform dissociation presents a defense mechanism related to a passive coping response.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
1M06039, research and development projectName: Centrum pro neuropsychiatrický výzkum traumatického stresu
Investor: Ministry of Education, Youth and Sports of the CR
PrintDisplayed: 30/5/2024 18:25