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@article{799733, author = {Švestka, Jaromír}, article_location = {Sweden}, article_number = {suppl. 1}, keywords = {sleep; deprivation; pharmacotherapy; therapy}, language = {eng}, issn = {0172-780X}, journal = {NEUROENDOCRINOLOGY LETTERS}, title = {Sleep deprivation therapy}, volume = {29}, year = {2008} }
TY - JOUR ID - 799733 AU - Švestka, Jaromír PY - 2008 TI - Sleep deprivation therapy JF - NEUROENDOCRINOLOGY LETTERS VL - 29 IS - suppl. 1 SP - 65-92 EP - 65-92 PB - Neuro Endocrinology Letters ISSN 0172–780X SN - 0172780X KW - sleep KW - deprivation KW - pharmacotherapy KW - therapy N2 - Sleep deprivation is a useful therapeutic option in the treatment of depressive disorders, especially in pharmacoresistant disorders. Its therapeutic efficacy in other indications has not, however, been confirmed. According to current knowledge, application of sleep therapy requires concomitant therapy to prevent early relapses of depression. Total sleep deprivation is the classic variant of its clinical use. Partial sleep deprivation has a somewhat less pronounced antidepressant effect, and the duration of sleep deprivation rather than application timing determines its therapeutic effect. The most reliable predictors of sleep deprivation efficacy are marked diurnal fluctuations of depressive mood, patient locomotor activity, and limbic hyperactivity in the central nervous system. The mechanism of the antidepressant effect of sleep deprivation remains unknown. ER -
ŠVESTKA, Jaromír. Sleep deprivation therapy. \textit{NEUROENDOCRINOLOGY LETTERS}. Sweden: Neuro Endocrinology Letters ISSN 0172–780X, 2008, roč.~29, suppl. 1, s.~65-92. ISSN~0172-780X.
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