CRHA, Igor, Pavel VENTRUBA, Martin HUSER, Jana ŽÁKOVÁ, Robert HUDEČEK a Jiří JARKOVSKÝ. Survival and infertility treatment in male cancer patients after sperm banking. Fertility and Sterility. 2009, roč. 91, č. 6, s. 2344-2348. ISSN 1556-5653.
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Základní údaje
Originální název Survival and infertility treatment in male cancer patients after sperm banking
Název česky Survival and infertility treatment in male cancer patients after sperm banking
Autoři CRHA, Igor (203 Česká republika, garant, domácí), Pavel VENTRUBA (203 Česká republika, domácí), Martin HUSER (203 Česká republika, domácí), Jana ŽÁKOVÁ (203 Česká republika, domácí), Robert HUDEČEK (203 Česká republika, domácí) a Jiří JARKOVSKÝ (203 Česká republika, domácí).
Vydání Fertility and Sterility, 2009, 1556-5653.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30214 Obstetrics and gynaecology
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 3.970
Kód RIV RIV/00216224:14110/09:00034393
Organizační jednotka Lékařská fakulta
UT WoS 000266801400009
Klíčová slova česky cryopreservation; semen; cancer survivors; male infertility
Klíčová slova anglicky cryopreservation; semen; cancer survivors; male infertility
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnil: Mgr. Michal Petr, učo 65024. Změněno: 6. 2. 2019 10:46.
Anotace
OBJECTIVE: The main aim of the study was to evaluate the relationship between sperm pathology and cancer diagnosis, determine the mortality rate, and evaluate the outcomes of the use of frozen sperm from the sperm bank. DESIGN: Prospective study. SETTING: University fertility center. PATIENT(S): A total of 619 male patients were referred for sperm freezing before gonadotoxic therapy from 1995 to 2006. INTERVENTION(S): Semen analysis, data verification in the National Oncological Register, assisted reproduction techniques, statistical evaluation. MAIN OUTCOME MEASURE(S): Cancer diagnosis and sperm pathology analysis, survival of patients and infertility treatment. RESULT(S): Malignant testicular cancer was diagnosed in 43.6% of patients, while malignant neoplasms of the lymphatic and haematopoietic tissues were found in 31.7% of patients. Azoospermia, or severe oligospermia were detected in 9.7% and 22.6% of patients, respectively. Until now, 32 patients (5.2%) have attended for infertility treatment. Cryopreserved semen was used in 28 couples (87.5%), 44 ICSI cycles resulted in 13 pregnancies. In total, 74 deaths (11.9%) were reported, 61 of them (82.4%) within 30 months of the cryopreservation of their sperm. CONCLUSION(S): Significant number of patients survived. Intrauterine insemination and ICSI with cryopreserved sperm resulted in deliveries.
Anotace česky
OBJECTIVE: The main aim of the study was to evaluate the relationship between sperm pathology and cancer diagnosis, determine the mortality rate, and evaluate the outcomes of the use of frozen sperm from the sperm bank. DESIGN: Prospective study. SETTING: University fertility center. PATIENT(S): A total of 619 male patients were referred for sperm freezing before gonadotoxic therapy from 1995 to 2006. INTERVENTION(S): Semen analysis, data verification in the National Oncological Register, assisted reproduction techniques, statistical evaluation. MAIN OUTCOME MEASURE(S): Cancer diagnosis and sperm pathology analysis, survival of patients and infertility treatment. RESULT(S): Malignant testicular cancer was diagnosed in 43.6% of patients, while malignant neoplasms of the lymphatic and haematopoietic tissues were found in 31.7% of patients. Azoospermia, or severe oligospermia were detected in 9.7% and 22.6% of patients, respectively. Until now, 32 patients (5.2%) have attended for infertility treatment. Cryopreserved semen was used in 28 couples (87.5%), 44 ICSI cycles resulted in 13 pregnancies. In total, 74 deaths (11.9%) were reported, 61 of them (82.4%) within 30 months of the cryopreservation of their sperm. CONCLUSION(S): Significant number of patients survived. Intrauterine insemination and ICSI with cryopreserved sperm resulted in deliveries.
Návaznosti
MSM0021622412, záměrNázev: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Akronym: INCHEMBIOL)
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální , regionální a lokální úrovni
VytisknoutZobrazeno: 22. 8. 2024 10:12