EFFECT OF BAROREFLEX ON BLOOD PRESSURE VARIABILITY

HONZÍKOVÁ, Klára, Hana HRSTKOVÁ, Jana ŠŤASTNÁ, Zuzana NOVÁKOVÁ, Nataša HONZÍKOVÁ, Bohumil FIŠER, Eva ZÁVODNÁ, Antoín KRTIČKA and Petr HONZÍK. EFFECT OF BAROREFLEX ON BLOOD PRESSURE VARIABILITY. In 17th Meeting of ES-PCR. 2008.

Basic information

• Original name: EFFECT OF BAROREFLEX ON BLOOD PRESSURE VARIABILITY
• Name in Czech: Vliv citlivosti baroreflexu na variabilitu krevního tlaku
• Authors: HONZÍKOVÁ, Klára, Hana HRSTKOVÁ, Jana ŠŤASTNÁ, Zuzana NOVÁKOVÁ, Nataša HONZÍKOVÁ, Bohumil FIŠER, Eva ZÁVODNÁ, Antoín KRTIČKA and Petr HONZÍK.
• Edition: 17th Meeting of ES-PCR, 2008.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: 30209 Paediatrics
• Country of publisher: Austria
• Confidentiality degree: is not subject to a state or trade secret
• Organization unit: Faculty of Medicine
• Keywords (in Czech): citlivost baroreflexu; variabilita krevního tlaku
• Keywords in English: baroreflex sensitivity; blood pressure variability
• Tags: baroreflex sensitivity, blood pressure variability
• Tags: International impact, Reviewed

Abstract

We studied 58 subjects (20-22 years). Systolic and diastolic blood pressures (SBP, DBP) and inter-beat intervals (IBI) were recorded beat-to-beat for 5 min (Finapres). BRS, and BRSf were determined by the spectral method at 0.1 Hz frequency range. To make a comparison of the quantitative effects of BRS and BRSf on SBPv possible, both variables were expressed as multiples of standard deviations: BRSsd = (BRS – mean BRS) / SD of BRS; BRSfsd = (BRSf – mean BRSf) / SD of BRSf. A negative correlation was found between SBPv and BRSsd (r = - 0.33, p<0.05), and between SBPv and BRSfsd (r = - 0.36, p<0.05). The multiple regression analysis showed higher regression coefficient of BRSfsd than of BRSsd (SBPv = 9.43 – 0.0052*IBI + 0.15*BRSsd – 1.85*BRSfsd, F = 2.92, p<0.05). The analysis revealed that the IBI independent index BRSf [mHz/mmHg] is a better indicator for evaluation of the effectivity of baroreflex sensitivity to suppress the SBP variability than the IBI dependent index BRS [ms/mmHg].

Abstract (in Czech)

Sledovali jsme 58 mladých zdravých osob (20-22 let). Srdeční intervaly (IBI), systolický (STK) a diastolický (DTK) krevní tlak byly zaznamenávány tep po tepu 5 min. Citlivost baroreflexu BRS a BRSf byla stanovena spektrální metodou v oblasti 0,1 Hz. Pro porovnání kvantitativního vlivu BRS a BRSf na variabilitu STK (STKv) byly indexy vyjádřeny jako násobky standardní odchylky: BRSsd = (BRS – průměr BRS) / SD BRS; BRSfsd = (BRSf – průměr BRSf) / SD BRSf. Byla nalezena negativní korelace mezi STKv a BRSsd (r = - 0,33, p<0,05) a STKv a BRSfsd (r = - 0,36, p<0,05). Multiregresní analýza ukázala vyšší regresní koeficient pro BRSfsd než Besed (STKv = 9,43 – 0,0052*IBI + 0,15*BRSsd – 1,85*BRSfsd, F = 2,92, p<0.05). Analýza odhalila, že na IBI nezávislý index BRSF (mHz/mmHg) je lepším indikátorem pro ohodnocení vlivu baroreflexu na utlumení krevního tlaku než IBI závislý index BRS.

Links

• MSM0021622402, plan (intention): Name: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases

• MSM0021630529, plan (intention): Name: Inteligentní systémy v automatizaci