Interference with hormonal signaling and dioxin-like activity elicited by pollutants in particulate and gaseous air fractions

NOVÁK, Jiří, Veronika JÁLOVÁ, JP GIESY and Klára HILSCHEROVÁ. Interference with hormonal signaling and dioxin-like activity elicited by pollutants in particulate and gaseous air fractions. Environment International. Amsterdam, The Netherlands: Elsevier, 2009, vol. 35, No 1, p. 43 – 49. ISSN 0160-4120.

Basic information

Original name

Interference with hormonal signaling and dioxin-like activity elicited by pollutants in particulate and gaseous air fractions

Name in Czech

Potenciál narušení hormonální regulace a aktivita dioxinového typu u polutantů z pevné a plynné frakce ovzduší

Authors

NOVÁK, Jiří (203 Czech Republic), Veronika JÁLOVÁ (203 Czech Republic), JP GIESY (840 United States of America) and Klára HILSCHEROVÁ (203 Czech Republic, guarantor)

Edition

Environment International, Amsterdam, The Netherlands, Elsevier, 2009, 0160-4120

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.786

RIV identification code

RIV/00216224:14310/09:00029254

Organization unit

Faculty of Science

UT WoS

000262218500007

Keywords (in Czech)

ovzduší; endocrinní disrupce; toxicita dioxinového typu; antiestrogenní; antiandrogenní

Keywords in English

air; endocrine disruption; dioxin-like toxicity; antiestrogenic; antiandrogenic

Tags

Air, antiandrogenic, antiestrogenic, dioxin-like toxicity, endocrine disruption

Tags

International impact, Reviewed

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Abstract

V originále

Interference with hormonal signaling and dioxin-like activity elicited by pollutants in particulate and gaseous air fractions. Traditionally, contamination of air has been evaluated primarily by chemical analyses of indicator contaminants and these studies have focused mainly on compounds associated with particulates. Some reports have shown that air contaminants can produce specific biological effects such as toxicity mediated by the aryl hydrocarbon receptor (AhR) or modulation of the endocrine system. This study assessed the dioxin-like toxicity, anti/estrogenicity, anti/androgenicity and anti/retinoic activity of both the particulate and gas phase fractions of air in two regions with different types of pollution sources and a background locality situated in an agricultural area of Central Europe.

In Czech

Studie dokumentuje potenciál narušení hormonální regulace a aktivity dioxinového typu u polutantů z pevné a plynné frakce ovzduší u vzorků ze dvou oblastí s různým typem zdrojů znečištění. Studie se zaměřuje na toxicitu dioxinového typu, anti/estrogenitu, anti/androgenitu a anti/retinoidní aktivitu.

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Links

GP525/05/P160, research and development project	Name: In vitro modely pro studium endokrinní disrupce - účinky tradičních a nových typů persistentních organických polutantů Investor: Czech Science Foundation, In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants
MSM0021622412, plan (intention)	Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL) Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
2B08036, research and development project	Name: Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů (Acronym: ENVISCREEN) Investor: Ministry of Education, Youth and Sports of the CR, New molecular biology and biochemical methods to monitor estrogens and other endocrine disruptors in the environment of the C.R.