BÁRTOVÁ, Eva, J. KREJČÍ, Roman HÁJEK, Andrea HARNIČAROVÁ and Stanislav KOZUBEK. Chromatin structure and epigenetics of tumour cells: a review. Cardiovascular & Hematological Disorders - Drug Targets. Netherlands: Bentham Science Publishers, 2009, vol. 9, No 1, p. 51-61. ISSN 1871-529X.
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Basic information
Original name Chromatin structure and epigenetics of tumour cells: a review.
Name in Czech Struktura chromatinu a epigenetika nádorových buněk
Authors BÁRTOVÁ, Eva (203 Czech Republic, guarantor), J. KREJČÍ (203 Czech Republic), Roman HÁJEK (203 Czech Republic), Andrea HARNIČAROVÁ (703 Slovakia) and Stanislav KOZUBEK (203 Czech Republic).
Edition Cardiovascular & Hematological Disorders - Drug Targets, Netherlands, Bentham Science Publishers, 2009, 1871-529X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/09:00028480
Organization unit Faculty of Science
Keywords (in Czech) chromatin; epigenetika
Keywords in English chromatin; epigenetics;
Tags chromatin, epigenetics
Tags International impact, Reviewed
Changed by Changed by: Mgr. Anna Potáčová, Ph.D., učo 44190. Changed: 1/4/2010 16:56.
Abstract
Tumour cells are characterized by karyotype instability, which is accompanied by specific events in the chromatin structure and epigenetic patterns. Epigenetics involves heritable changes in the physical and biochemical state of chromatin, which have no effect on DNA sequences; therefore, changes in the nuclear radial arrangement of chromosomes can also be considered epigenetic events.
Abstract (in Czech)
Tato publikace se zabývá strukturou chromatinu a epigenetikou nádorových buněk, pro které je charakteristická nestabilita karyotypu.
Links
AV0Z50040507, plan (intention)Name: Biofyzika dynamických struktur a funkcí biologických systémů
GA204/06/0978, research and development projectName: Změny v postranslačních modifikacích histonů po působení inhibitorů histon deacetyláz a po indukci buněčné diferenciace
LC06027, research and development projectName: Univerzitní výzkumné centrum - Česká myelomová skupina (Acronym: LC MGUS)
Investor: Ministry of Education, Youth and Sports of the CR, University Research Centre - Czech Myeloma Group
LC535, research and development projectName: Dynamika a organizace chromosomů během buněčného cyklu v normě a patologii
Investor: Ministry of Education, Youth and Sports of the CR, Dynamika a organizace chromosomů během buněčného cyklu v normě a patologii
1QS500040508, research and development projectName: Methylace histonu H3 v granulocytech jako prognostický marker remise chronické myeloidní leukémie
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