J 2007

Direct repair (nerve grafting), neurotization, and end-to-side neurorrhaphy in the treatment of brachial plexus injury

HANINEC, Pavel, Filip ŠÁMAL, Robert TOMÁŠ, Ladislav HOUŠŤAVA, Petr DUBOVÝ et. al.

Basic information

Original name

Direct repair (nerve grafting), neurotization, and end-to-side neurorrhaphy in the treatment of brachial plexus injury

Name in Czech

Přímá reparace poškozeného brachiálního plexu neurotizací a end-to-side anastomózou

Authors

HANINEC, Pavel (203 Czech Republic), Filip ŠÁMAL (203 Czech Republic), Robert TOMÁŠ (203 Czech Republic), Ladislav HOUŠŤAVA (203 Czech Republic) and Petr DUBOVÝ (203 Czech Republic, guarantor)

Edition

Journal of Neurosurgery, 2007, 0022-3085

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.990

RIV identification code

RIV/00216224:14110/07:00028062

Organization unit

Faculty of Medicine

UT WoS

000244864700006

Keywords in English

brachial plexus; end-to-side neurorrhaphy; neurotization; nerve graft; electromyography; peripheral nerve
Změněno: 26/6/2009 11:24, prof. RNDr. Petr Dubový, CSc.

Abstract

V originále

Object. The authors present the long-term results of nerve grafting and neurotization procedures in their group of patients with brachial plexus injuries and compare the results of "classic" methods of nerve repair with those of end-to-side neurorrhaphy. Methods. Between 1994 and 2006, direct repair (nerve grafting), neurotization, and end-to-side neurorrhaphy were performed in 168 patients, 95 of whom were followed up for at least 2 years after surgery. Successful results were achieved in 79% of cases after direct repair and in 56% of cases after end-to-end neurotization. The results of neurotization depended on the type of the donor nerve used. In patients who underwent neurotization of the axillary and the musculocutaneous nerves, the use of intraplexal nerves (motor branches of the brachial plexus) as donors of motor fibers was associated with a significantly higher success rate than the use of extraplexal nerves (81% compared with 49%, respectively, p = 0.003). Because of poor functional results of axillary nerve neurotization using extraplexal nerves (success rate 47.4%), the authors used end-to-side neurorrhaphy in 14 cases of incomplete avulsion. The success rate for end-to-side neurorrhaphy using the axillary nerve as a recipient was 64.3%, similar to that for neurotization using intraplexal nerves (68.4%) and better than that achieved using extraplexal nerves (47.4%, p = 0.19). Conclusions. End-to-side neurorrhaphy offers an advantage over classic neurotization in not requiring sacrifice of any of the surrounding nerves or the fascicles of the ulnar nerve. Typical synkinesis of muscle contraction innervated by the recipient nerve with contraction of muscles innervated by the donor was observed in patients after end-to-side neurorrhaphy.

In Czech

Autoři prezentují dlouhodobé výsledky rekonstrukčních operací poškozeného brachiálního plexu metodou přímé neurotizace nebo end-to-side anastomózou. End-to-side anastomóza poskytuje nové možnosti při rekonstrukci brachiálního plexu.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
NF6658, research and development project
Name: Alternativní přístupy v rekonstrukci pažní pleteně a experimentální vyhodnocení účinku neurotrofinů na přímou a kolaterální reinervaci
Investor: Ministry of Health of the CR, Alternative approaches in brachial plexus reconstruction and experimental evaluation of various neurotrophic factors action on direct and collateral reinnervati