Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay

GRACIA, T., P.D. JONES, E.B. HIGLEY, Klára HILSCHEROVÁ, J. NEWSTED, M.B. MURPHY, A.K.Y. CHAN, X.W. ZHANG, M. HECKER, P.K.S. LAM, R.S.S. WU and J.P. GIESY. Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay. Environmental Science and Pollution Research. Heidelberg: Springer, 2008, vol. 15, No 4, 13 pp. ISSN 0944-1344.

Basic information

Original name

Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay

Name in Czech

Modulace steroidogeneze v H295R po expozici vzorků z Hong Kong

Authors

GRACIA, T. (840 United States of America), P.D. JONES (840 United States of America), E.B. HIGLEY (840 United States of America), Klára HILSCHEROVÁ (203 Czech Republic, guarantor), J. NEWSTED (840 United States of America), M.B. MURPHY (840 United States of America), A.K.Y. CHAN (840 United States of America), X.W. ZHANG (840 United States of America), M. HECKER (840 United States of America), P.K.S. LAM (840 United States of America), R.S.S. WU (840 United States of America) and J.P. GIESY (840 United States of America)

Edition

Environmental Science and Pollution Research, Heidelberg, Springer, 2008, 0944-1344

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.492

RIV identification code

RIV/00216224:14310/08:00028087

Organization unit

Faculty of Science

UT WoS

000256910500008

Keywords (in Czech)

H295R; endokrinní disrupce; in vitro

Keywords in English

H295R; endocrine disruption; in vitro

Tags

endocrine disruption, H295R, in vitro

Tags

International impact, Reviewed

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Abstract

V originále

This complex study investigates modulation of steroidogenesis in model adrenocortical cell line H295R by samples from coastal waters and sewage effluents of Hong Kong. It shows significant modulations of several steroidogenic enzymes by the tested environmental samples.

In Czech

Tato komplexní studie zkoumá ovlivnění steroidogeneze v buněčném modelu z kůry nadledvinek H295R po expozici vzorků povrchových a odpadních vod z oblasti Hong Kongu. Výsledky ukazují významnou modulaci některých klíčových enzymů steroidogeneze po expozici vzorků z prostředí.

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Links

MSM0021622412, plan (intention)	Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL) Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
2B08036, research and development project	Name: Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů (Acronym: ENVISCREEN) Investor: Ministry of Education, Youth and Sports of the CR, New molecular biology and biochemical methods to monitor estrogens and other endocrine disruptors in the environment of the C.R.