MIKULA, Přemysl, Kamila KRUŽÍKOVÁ, Radka DOBŠÍKOVÁ, Danka HARUŠTIAKOVÁ and Zdeňka SVOBODOVÁ. Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio). Acta Veterinaria Brno. Brno: Univ. of Vet. and Pharmac Sc., 2009, vol. 78, No 2, p. 319-326. ISSN 0001-7213.
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Basic information
Original name Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)
Name in Czech Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)
Authors MIKULA, Přemysl (203 Czech Republic), Kamila KRUŽÍKOVÁ (203 Czech Republic), Radka DOBŠÍKOVÁ (203 Czech Republic), Danka HARUŠTIAKOVÁ (703 Slovakia, guarantor) and Zdeňka SVOBODOVÁ (203 Czech Republic).
Edition Acta Veterinaria Brno, Brno, Univ. of Vet. and Pharmac Sc. 2009, 0001-7213.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10511 Environmental sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.403
RIV identification code RIV/00216224:14310/09:00036187
Organization unit Faculty of Science
UT WoS 000267788000019
Keywords (in Czech) Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens
Keywords in English Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens
Tags FISH, parabens, preservatives, sex differentiation, vitellogenin, xeno-oestrogens
Tags International impact, Reviewed
Changed by Changed by: RNDr. Danka Haruštiaková, Ph.D., učo 163612. Changed: 23/2/2010 21:17.
Abstract
The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.
Abstract (in Czech)
The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.
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MSM0021622412, plan (intention)Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
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