2009
Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)
MIKULA, Přemysl, Kamila KRUŽÍKOVÁ, Radka DOBŠÍKOVÁ, Danka HARUŠTIAKOVÁ, Zdeňka SVOBODOVÁ et. al.Základní údaje
Originální název
Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)
Název česky
Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)
Autoři
MIKULA, Přemysl (203 Česká republika), Kamila KRUŽÍKOVÁ (203 Česká republika), Radka DOBŠÍKOVÁ (203 Česká republika), Danka HARUŠTIAKOVÁ (703 Slovensko, garant) a Zdeňka SVOBODOVÁ (203 Česká republika)
Vydání
Acta Veterinaria Brno, Brno, Univ. of Vet. and Pharmac Sc. 2009, 0001-7213
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
10511 Environmental sciences
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 0.403
Kód RIV
RIV/00216224:14310/09:00036187
Organizační jednotka
Přírodovědecká fakulta
UT WoS
000267788000019
Klíčová slova česky
Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens
Klíčová slova anglicky
Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 23. 2. 2010 21:17, RNDr. Danka Haruštiaková, Ph.D.
V originále
The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.
Česky
The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group.
Návaznosti
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