k 2009

Bayesian Estimation of Mean Sojourn Time and Sensitivity in the Czech Organized Mammography Screening Programme

BUREŠOVÁ, Lucie, Ondřej MÁJEK, Jan DANEŠ, Helena BARTOŇKOVÁ, Miroslava SKOVAJSOVÁ et. al.

Základní údaje

Originální název

Bayesian Estimation of Mean Sojourn Time and Sensitivity in the Czech Organized Mammography Screening Programme

Autoři

BUREŠOVÁ, Lucie, Ondřej MÁJEK, Jan DANEŠ, Helena BARTOŇKOVÁ, Miroslava SKOVAJSOVÁ a Ladislav DUŠEK

Vydání

Sixth Workshop on BAYESIAN INFERENCE IN STOCHASTIC PROCESSES, 2009

Další údaje

Typ výsledku

Prezentace na konferencích

Utajení

není předmětem státního či obchodního tajemství

Organizační jednotka

Institut biostatistiky a analýz

Příznaky

Mezinárodní význam
Změněno: 14. 12. 2010 16:53, RNDr. Ondřej Májek, Ph.D.

Anotace

V originále

Organized breast cancer screening programme in the Czech Republic was initiated in September 2002. Free biennial preventive mammography examinations are offered to women aged 45-69. By year 2007 1,067,836 women were screened (more than 50% of the target population) in 1,611,582 examinations. A total of 7,835 cases of breast cancer were detected. Important parameters in assessing the quality of the programme and natural history of breast cancer are: mean duration of the preclinical screen-detectable phase (the carcinoma is without clinical signs but it could be found by the screening test - mammography), which is called mean sojourn time, and sensitivity of mammography (capability of the test to detect cancer). These parameters are not directly observable; however, they can be estimated using mathematical models. Both parameters were estimated for different age groups of women in target population. Simple tree-state Markov model with states: disease free - preclinical screen-detectable - clinical disease was developed and utilized for estimation. Analysis was performed using WinBUGS programme.