| KOVÁŘOVÁ, Lucie, Ivana BUREŠOVÁ, Tomáš BÜCHLER, Renata SUSKÁ, Luděk POUR, Lenka ZAHRADOVÁ, Miroslav PENKA and Roman HÁJEK. Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance. Neoplasma. Blarislava, Slovakia: Slovak Academy of Sciences, 2009, vol. 56, No 6, p. 526-532. ISSN 0028-2685. |
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@article{846121,
author = {Kovářová, Lucie and Burešová, Ivana and Büchler, Tomáš and Suská, Renata and Pour, Luděk and Zahradová, Lenka and Penka, Miroslav and Hájek, Roman},
article_location = {Blarislava, Slovakia},
article_number = {6},
keywords = {flow cytometry; plasma cells; monoclonal gammopathy; multiple myeloma},
language = {eng},
issn = {0028-2685},
journal = {Neoplasma},
title = {Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance},
url = {http://www.neoplasma.sk/},
volume = {56},
year = {2009}
}
TY - JOUR
ID - 846121
AU - Kovářová, Lucie - Burešová, Ivana - Büchler, Tomáš - Suská, Renata - Pour, Luděk - Zahradová, Lenka - Penka, Miroslav - Hájek, Roman
PY - 2009
TI - Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance
JF - Neoplasma
VL - 56
IS - 6
SP - 526-532
EP - 526-532
PB - Slovak Academy of Sciences
SN - 00282685
KW - flow cytometry
KW - plasma cells
KW - monoclonal gammopathy
KW - multiple myeloma
UR - http://www.neoplasma.sk/
N2 - The aim of this study was to find possibilities and limits of multicolour flow cytometry in diagnostics of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) and to identify parameters that could be used to differentiate between these two disorders. In bone marrow, the percentage of residual polyclonal CD19+ plasma cells was higher (p<0.001) and the percentage of malignant monoclonal CD56+ plasma cells was lower (p<0.001) in MGUS than in MM. The relative counts of CD19+ plasma cells permitted unequivocal differentiation of MGUS from all clinical stages of MM. Flow cytometry is relatively quick and effective method for analysis of plasma cells thus immunophenotyping can significantly contribute to the differential diagnosis of plasma cell proliferations.
ER -
KOVÁŘOVÁ, Lucie, Ivana BUREŠOVÁ, Tomáš BÜCHLER, Renata SUSKÁ, Luděk POUR, Lenka ZAHRADOVÁ, Miroslav PENKA and Roman HÁJEK. Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance. \textit{Neoplasma}. Blarislava, Slovakia: Slovak Academy of Sciences, 2009, vol.~56, No~6, p.~526-532. ISSN~0028-2685.
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