HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT
STUDY FOR SCORING OF THE DIC

J 2008

HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC

LIPOVÝ, Břetislav, Yvona KALOUDOVÁ, Miloslava MATÝŠKOVÁ, Miroslav PENKA, Hana ŘIHOVÁ et. al.

Základní údaje

Originální název

HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC

Název česky

Hemokoagulační poruchy u těžce popálených pacientů: pilotní studie ke skórování DIC

Autoři

LIPOVÝ, Břetislav (203 Česká republika, garant), Yvona KALOUDOVÁ (203 Česká republika), Miloslava MATÝŠKOVÁ (203 Česká republika), Miroslav PENKA (203 Česká republika), Hana ŘIHOVÁ (203 Česká republika) a Pavel BRYCHTA (203 Česká republika)

Vydání

Acta chirurgiae plasticae, Praha, 2008, 1803-6597

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/08:00036699

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

DIC haemocoagulation assesment burn trauma D dimers

Příznaky

Recenzováno

Změněno: 4. 2. 2010 20:50, prof. MUDr. Břetislav Lipový, Ph.D., MBA, LL.M.

Anotace

V originále

Goal of the study. To apply results of the hemocoagulation parameters to the DIC (disseminated intravascular coagulation) score system. Compare parameters of the DIC score in patients with extensive burn trauma (hospitalized at the Intensive Care Unit, ICU) and patients with lesser extent of burn injury (hospitalized at the standard unit). To use these data within the evidence based medicine for the prediction of organ damage and multi organ failure. Type of study. Prospective study. Material and methods. We have included total of 36 patients in the group within four months. Twelve patients were hospitalized at the ICU, 24 patients were hospitalized at the intermedial care and standard unit. Repeatedly, we have taken blood from patients to evaluate the hemocoagulation parameters. In patients hospitalized at the ICU, the blood was taken from the central vein (prior to the drawn, the access was flushed with 100ml of F1/1, the blood was taken from different access than from the one administering heparin), in patients hospitalized at the standard unit the blood was taken from a peripheral vein. The results were then put into the tables established according to the ISTH (International Society on Thrombosis and Hemostasis). Next, the DIC score was calculated to predict severity of hemocoagulation balance disorders in burn trauma, or occurrence of complications during the treatment. Results. Part 1: We have evaluated 12 patients (4 females) hospitalized at the ICU. At the day of injury the overt DIC score reached 1.25 (0 3), fifth day after the injury the average value of overt DIC score was 1.83 (0 3), one day after the autotransplantation it was 2.08 (0 3) and at the day of discharge from the hospital 0. In the deceased patient the DIC score reached value of 2. Part 2: We evaluated 24 patients (10 females) hospitalized at the standard unit. The extent of their burn injury was 5.9% TBSA (0.5 12% TBSA), age 49.13 years (17 94 years). At the day of injury the overt DIC score reached 0.25 (0 2). Fifth day after the injury the average value of overt DIC score was 1.66 (0 2). Day after the autotransplantation it was 1.83 (0 3) and at the day of discharge 0.02 (0 2). Conclusion. During the treatment of the patients with various extent of burn injury, none of the patients scores reached values that would mean occurrence of obvious overt DIC.

Citovat

LIPOVÝ, Břetislav, Yvona KALOUDOVÁ, Miloslava MATÝŠKOVÁ, Miroslav PENKA, Hana ŘIHOVÁ a Pavel BRYCHTA. HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC. Acta chirurgiae plasticae. Praha, 2008, roč. 50, č. 4, s. 115-118, 120 s. ISSN 1803-6597.

@article{847629,
   author = {Lipový, Břetislav and Kaloudová, Yvona and Matýšková, Miloslava and Penka, Miroslav and Řihová, Hana and Brychta, Pavel and Penka, Miroslav and Řihová, Hana and Brychta, Pavel},
   article_location = {Praha},
   article_number = {4},
   keywords = {DIC haemocoagulation assesment burn trauma D dimers},
   language = {eng},
   issn = {1803-6597},
   journal = {Acta chirurgiae plasticae},
   title = {HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC},
   volume = {50},
   year = {2008}
}

TY  - JOUR
ID  - 847629
AU  - Lipový, Břetislav - Kaloudová, Yvona - Matýšková, Miloslava - Penka, Miroslav - Řihová, Hana - Brychta, Pavel - Penka, Miroslav - Řihová, Hana - Brychta, Pavel
PY  - 2008
TI  - HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC
JF  - Acta chirurgiae plasticae
VL  - 50
IS  - 4
SP  - 115-118
EP  - 115-118
SN  - 18036597
KW  - DIC haemocoagulation assesment burn trauma D dimers
N2  - Goal of the study. To apply results of the hemocoagulation parameters to the DIC (disseminated intravascular coagulation) score system. Compare parameters of the DIC score in patients with extensive burn trauma (hospitalized at the Intensive Care Unit, ICU) and patients with lesser extent of burn injury (hospitalized at the standard unit). To use these data within the evidence based medicine for the prediction of organ damage and multi organ failure. Type of study. Prospective study. Material and methods. We have included total of 36 patients in the group within four months. Twelve patients were hospitalized at the ICU, 24 patients were hospitalized at the intermedial care and standard unit. Repeatedly, we have taken blood from patients to evaluate the hemocoagulation parameters. In patients hospitalized at the ICU, the blood was taken from the central vein (prior to the drawn, the access was flushed with 100ml of F1/1, the blood was taken from different access than from the one administering heparin), in patients hospitalized at the standard unit the blood was taken from a peripheral vein. The results were then put into the tables established according to the ISTH (International Society on Thrombosis and Hemostasis). Next, the DIC score was calculated to predict severity of hemocoagulation balance disorders in burn trauma, or occurrence of complications during the treatment. Results. Part 1: We have evaluated 12 patients (4 females) hospitalized at the ICU. At the day of injury the overt DIC score reached 1.25 (0 3), fifth day after the injury the average value of overt DIC score was 1.83 (0 3), one day after the autotransplantation it was 2.08 (0 3) and at the day of discharge from the hospital 0. In the deceased patient the DIC score reached value of 2. Part 2: We evaluated 24 patients (10 females) hospitalized at the standard unit. The extent of their burn injury was 5.9% TBSA (0.5 12% TBSA), age 49.13 years (17 94 years). At the day of injury the overt DIC score reached 0.25 (0 2). Fifth day after the injury the average value of overt DIC score was 1.66 (0 2). Day after the autotransplantation it was 1.83 (0 3) and at the day of discharge 0.02 (0 2). Conclusion. During the treatment of the patients with various extent of burn injury, none of the patients scores reached values that would mean occurrence of obvious overt DIC.
ER  -

LIPOVÝ, Břetislav, Yvona KALOUDOVÁ, Miloslava MATÝŠKOVÁ, Miroslav PENKA, Hana ŘIHOVÁ a Pavel BRYCHTA. HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC. \textit{Acta chirurgiae plasticae}. Praha, 2008, roč.~50, č.~4, s.~115-118, 120 s. ISSN~1803-6597.

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