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@proceedings{857834,
author = {Vařecha, Miroslav and Ulman, Vladimír and Matula, Pavel and Kozubek, Michal},
booktitle = {Analytical Cytometry V},
keywords = {localization prediction;AIF;endonuclease G;AMID;fluorescence microscopy;docking;protein structure modeling},
language = {eng},
isbn = {978-80-254-2561-9},
title = {Prediction of localization and interactions of apoptotic proteins},
year = {2009}
}
TY - CONF
ID - 857834
AU - Vařecha, Miroslav - Ulman, Vladimír - Matula, Pavel - Kozubek, Michal
PY - 2009
TI - Prediction of localization and interactions of apoptotic proteins
SN - 9788025425619
KW - localization prediction;AIF;endonuclease G;AMID;fluorescence microscopy;docking;protein structure modeling
N2 - We found the AMID protein to be cytoplasmic, most probably incorporated into the cytoplasmic side of the lipid membranes. Bioinformatic predictions were conducted to analyze the interactions of the studied proteins with each other and with other possible partners. We conducted molecular modeling of proteins with unknown 3D structures. These models were then refined by MolProbity server and employed in molecular docking simulations of interactions. Our results show data acquired using a combination of modern in silico methods and image analysis to understand the localization, interactions and functions of proteins AMID, AIF, endonuclease G, and other apoptosis-related proteins.
ER -
VAŘECHA, Miroslav, Vladimír ULMAN, Pavel MATULA a Michal KOZUBEK. Prediction of localization and interactions of apoptotic proteins. In \textit{Analytical Cytometry V}. 2009. ISBN~978-80-254-2561-9.
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