Protein engineering of carbohydrate binding proteins - understanding the recognition phenomena

WIMMEROVÁ, Michaela. Protein engineering of carbohydrate binding proteins - understanding the recognition phenomena. In FEBS Journal. Oxford: Wiley-Blackwell, 2009, p. 87. ISSN 1742-464X.

Basic information

Original name

Protein engineering of carbohydrate binding proteins - understanding the recognition phenomena

Name in Czech

Proteinové inženýrství bílkovin vázajících sacharidy - porozumění rozpoznávacího mechanismu

Authors

WIMMEROVÁ, Michaela

Edition

Oxford, FEBS Journal, p. 87-87, 2009

Publisher

Wiley-Blackwell

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Other information

Language

English

Type of outcome

Proceedings paper

Field of Study

10610 Biophysics

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 3.042

Organization unit

Faculty of Science

ISSN

UT WoS

000267069900237

Keywords (in Czech)

proteinové inženýrství; lektin;patogen

Keywords in English

protein engineering;lectin; pathogen

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Abstract

In the original language

The contribution is focused on few examples where a combination of experimental methods (isothermal titration microcalorimetry, surface plasmon resonance, X-ray crystallography) with computational approaches can bring a significant profit for better understanding of protein-carbohydrate interactions on molecular level. Insight into structure correlation with function analysis of high-affinity lectins allows for construction of carbohydrate-binding proteins with tuned affinity and specificity for biotechnology and bioanalytical purposes.

In Czech

Příspěvek je věnován některým příkladům, kde experimentální metody spolu s teoretickými nástroji pomáhají lepšímu porozumění interakcím mezi proteiny a sacharidy.

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Links

GA303/09/1168, research and development project	Name: Lektiny z lidských patogenů - struktura, funkce, inženýrství Investor: Czech Science Foundation, Lectins from human pathogens - structure, function, engineering
MSM0021622413, plan (intention)	Name: Proteiny v metabolismu a při interakci organismů s prostředím Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment