| LUKÁŠ, Zdeněk, Jan MAŇÁK, Josef BEDNAŘÍK a M. SCHREIBER. Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders. Scripta Medica. Brno: Masarykova univerzita, 2009, roč. 82, č. 3, s. 202-212. ISSN 1211-3395. |
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@article{863753,
author = {Lukáš, Zdeněk and Maňák, Jan and Bednařík, Josef and Schreiber, M.},
article_location = {Brno},
article_number = {3},
keywords = {critical illness polyneuropathy; critical illness myopathy; diagnosis; biopsy; follow-up study},
language = {eng},
issn = {1211-3395},
journal = {Scripta Medica},
title = {Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders},
volume = {82},
year = {2009}
}
TY - JOUR
ID - 863753
AU - Lukáš, Zdeněk - Maňák, Jan - Bednařík, Josef - Schreiber, M.
PY - 2009
TI - Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders
JF - Scripta Medica
VL - 82
IS - 3
SP - 202-212
EP - 202-212
PB - Masarykova univerzita
SN - 12113395
KW - critical illness polyneuropathy
KW - critical illness myopathy
KW - diagnosis
KW - biopsy
KW - follow-up study
N2 - Histopathological analysis of 52 muscle biopsies from 43 adult critically ill patients was performed to determine the differential diagnosis and course of neuromuscular involvement in critically ill patients suffering from critical illness polyneuropathy or myopathy. The first histopathological examination in all 43 patients revealed signs of neuropathy in 2 biopsies, myopathy in 19 biopsies, and neuromyopathy in 18, including type 2 fibre atrophy. A repeat study of 9 patients showed that the histopathological features changed in all cases. A second biopsy performed several months or years after the first revealed that myopathic features had regressed and either recovery to normal histopathological findings had occurred or evidence of a persistent neurogenic lesion was found. The results indicate that muscle involvement in critically ill patients is reversible.
ER -
LUKÁŠ, Zdeněk, Jan MAŇÁK, Josef BEDNAŘÍK a M. SCHREIBER. Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders. \textit{Scripta Medica}. Brno: Masarykova univerzita, 2009, roč.~82, č.~3, s.~202-212. ISSN~1211-3395.
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