Towards Modeling and Therapy of Genetic Diseases Using
Pluripotent Stem Cells

C 2011

Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells

DVOŘÁK, Petr

Základní údaje

Originální název

Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells

Autoři

DVOŘÁK, Petr (752 Švédsko, garant, domácí)

Vydání

New York, USA, Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo, od s. 65-76, 12 s. Stem Cell Biology and Regenerative Medicine, 2011

Nakladatel

Humana Press

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

Genetika a molekulární biologie

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

URL

Kód RIV

RIV/00216224:14110/11:00058852

Organizační jednotka

Lékařská fakulta

ISBN

978-1-60761-958-1

Klíčová slova anglicky

pluripotent stem cells; genetic diseases; therapy

Změněno: 2. 4. 2013 15:53, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.

Návaznosti

LC06034, projekt VaV

Název: Regulace morfogeneze rostlinných buněk a orgánů

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Regulace morfogeneze rostlinných buněk a orgánů

MSM0021622430, záměr

Název: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie

Citovat

DVOŘÁK, Petr. Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells. In Kristina Hug, Göran Hermerén. Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo. New York, USA: Humana Press, 2011, s. 65-76. Stem Cell Biology and Regenerative Medicine. ISBN 978-1-60761-958-1.

@inbook{869298,
   author = {Dvořák, Petr},
   address = {New York, USA},
   booktitle = {Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo},
   editor = {Kristina Hug, Göran Hermerén},
   keywords = {pluripotent stem cells; genetic diseases; therapy},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {New York, USA},
   isbn = {978-1-60761-958-1},
   pages = {65-76},
   publisher = {Humana Press},
   title = {Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells},
   url = {http://www.springer.com/life+sciences/book/978-1-60761-958-1},
   year = {2011}
}

TY  - CHAP
ID  - 869298
AU  - Dvořák, Petr
PY  - 2011
TI  - Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells
VL  - Stem Cell Biology and Regenerative Medicine
PB  - Humana Press
CY  - New York, USA
SN  - 9781607619581
KW  - pluripotent stem cells
KW  - genetic diseases
KW  - therapy
UR  - http://www.springer.com/life+sciences/book/978-1-60761-958-1
N2  - For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.
ER  -

DVOŘÁK, Petr. Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells. In Kristina Hug, Göran Hermerén. \textit{Translational Stem Cell Research : Issues Beyond the Debate on the Moral Status of the Human Embyo}. New York, USA: Humana Press, 2011, s.~65-76. Stem Cell Biology and Regenerative Medicine. ISBN~978-1-60761-958-1.

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