Bullous pemphigoid and internal diseases: A case-control study.

J 2010

Bullous pemphigoid and internal diseases: A case-control study.

JEDLIČKOVÁ, Hana, Miloslav HLUBINKA, Tomáš PAVLÍK, Věra SEMRÁDOVÁ, Eva BUDINSKÁ et. al.

Základní údaje

Originální název

Bullous pemphigoid and internal diseases: A case-control study.

Autoři

JEDLIČKOVÁ, Hana (203 Česká republika, garant), Miloslav HLUBINKA (203 Česká republika), Tomáš PAVLÍK (203 Česká republika), Věra SEMRÁDOVÁ (203 Česká republika), Eva BUDINSKÁ (703 Slovensko) a Zdeněk VLAŠÍN (203 Česká republika)

Vydání

European Journal of Dermatology, Francie, John Libbey Eurotext, 2010, 1167-1122

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Francie

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.421

Kód RIV

RIV/00216224:14110/10:00043272

Organizační jednotka

Lékařská fakulta

UT WoS

000274218000015

Klíčová slova anglicky

bullous pemphigoid; cancer; diabetes mellitus; etiopathogenesis; neurological disorder

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 8. 2010 11:17, RNDr. Tomáš Pavlík, Ph.D.

Anotace

V originále

To study associations of bullous pemphigoid (BP) with internal diseases, we conducted a retrospective case control study assessing the frequency of selected diseases: diabetes mellitus, neurological diseases, malignant tumors, benign prostate hyperplasia, hypertension and ischemic heart disease in patients with BP. 89 atients with BP, whose data were retrieved from the register of the Centre of bullous diseases from the period of 1991-2006, were matched with 89 controls of the same age and gender, recruited from patients treated for other skin diseases. The frequency of internal diseases at the time of the onset of BP was evaluated by unconditional logistic regression adjusted for age and gender and maximum likelihood test for contingency tables. Neurological disease was found in 42.7% of the patients and in 19.1% of controls. This difference was statistically significant (p value = 0.001). Moreover, regression analysis has shown that patients with neurological disease in the age group > 80 years have significantly higher risk of pemphigoid than patients without neurological disease (odds ratio 10.55; 95% confidence interval 2.68 to 41.49). Most frequent were cerebral stroke in men and dementia in women. For other diseases and other age groups, no statistically significant influence was found.

Citovat

JEDLIČKOVÁ, Hana, Miloslav HLUBINKA, Tomáš PAVLÍK, Věra SEMRÁDOVÁ, Eva BUDINSKÁ a Zdeněk VLAŠÍN. Bullous pemphigoid and internal diseases: A case-control study. European Journal of Dermatology. Francie: John Libbey Eurotext, 2010, roč. 20, č. 1, s. 96-101. ISSN 1167-1122.

@article{869402,
   author = {Jedličková, Hana and Hlubinka, Miloslav and Pavlík, Tomáš and Semrádová, Věra and Budinská, Eva and Vlašín, Zdeněk},
   article_location = {Francie},
   article_number = {1},
   keywords = {bullous pemphigoid; cancer; diabetes mellitus; etiopathogenesis; neurological disorder},
   language = {eng},
   issn = {1167-1122},
   journal = {European Journal of Dermatology},
   title = {Bullous pemphigoid and internal diseases: A case-control study.},
   volume = {20},
   year = {2010}
}

TY  - JOUR
ID  - 869402
AU  - Jedličková, Hana - Hlubinka, Miloslav - Pavlík, Tomáš - Semrádová, Věra - Budinská, Eva - Vlašín, Zdeněk
PY  - 2010
TI  - Bullous pemphigoid and internal diseases: A case-control study.
JF  - European Journal of Dermatology
VL  - 20
IS  - 1
SP  - 96-101
EP  - 96-101
PB  - John Libbey Eurotext
SN  - 11671122
KW  - bullous pemphigoid
KW  - cancer
KW  - diabetes mellitus
KW  - etiopathogenesis
KW  - neurological disorder
N2  - To study associations of bullous pemphigoid (BP) with internal diseases, we conducted a retrospective case control study assessing the frequency of selected diseases: diabetes mellitus, neurological diseases, malignant tumors, benign prostate hyperplasia, hypertension and ischemic heart disease in patients with BP. 89 atients with BP, whose data were retrieved from the register of the Centre of bullous diseases from the period of 1991-2006, were matched with 89 controls of the same age and gender, recruited from patients treated for other skin diseases. The frequency of internal diseases at the time of the onset of BP was evaluated by unconditional logistic regression adjusted for age and gender and maximum likelihood test for contingency tables. Neurological disease was found in 42.7% of the patients and in 19.1% of controls. This difference was statistically significant (p value = 0.001). Moreover, regression analysis has shown that patients with neurological disease in the age group > 80 years have significantly higher risk of pemphigoid than patients without neurological disease (odds ratio 10.55; 95% confidence interval 2.68 to 41.49). Most frequent were cerebral stroke in men and dementia in women. For other diseases and other age groups, no statistically significant influence was found.
ER  -

JEDLIČKOVÁ, Hana, Miloslav HLUBINKA, Tomáš PAVLÍK, Věra SEMRÁDOVÁ, Eva BUDINSKÁ a Zdeněk VLAŠÍN. Bullous pemphigoid and internal diseases: A case-control study. \textit{European Journal of Dermatology}. Francie: John Libbey Eurotext, 2010, roč.~20, č.~1, s.~96-101. ISSN~1167-1122.

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