| SOUCKOVA, E., A. KOVARIK, Ladislav DUŠEK, L. HUMPOLIKOVA-ADAMKOVA, L. LAUEROVA a E. KREJCI. Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells. Neoplasma. 2009, roč. 56, č. 5, 8 s. ISSN 0028-2685. |
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@article{874065,
author = {Souckova, E. and Kovarik, A. and Dušek, Ladislav and HumpolikovaandAdamkova, L. and Lauerova, L. and Krejci, E.},
article_number = {5},
keywords = {suppressor of STAT signaling; STAT1; breast cancer; interferon; cell resistance},
language = {eng},
issn = {0028-2685},
journal = {Neoplasma},
title = {Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells},
volume = {56},
year = {2009}
}
TY - JOUR
ID - 874065
AU - Souckova, E. - Kovarik, A. - Dušek, Ladislav - Humpolikova-Adamkova, L. - Lauerova, L. - Krejci, E.
PY - 2009
TI - Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells
JF - Neoplasma
VL - 56
IS - 5
SN - 00282685
KW - suppressor of STAT signaling
KW - STAT1
KW - breast cancer
KW - interferon
KW - cell resistance
N2 - The resistance to interferons (IFNs) limits their anticancer therapeutic efficacy. Here we studied the antiproliferative effect of interferon gamma in relation to SOCS3 expression in a panel of breast cancer cell lines and normal mammary epithelial cells. Compared to normal cells most breast cancer lines (7/8) were highly resistant to IFN-gamma.
ER -
SOUCKOVA, E., A. KOVARIK, Ladislav DUŠEK, L. HUMPOLIKOVA-ADAMKOVA, L. LAUEROVA a E. KREJCI. Reduced inducibility of SOCS3 by interferon gamma associates with higher resistance of human breast cancer lines as compared to normal mammary epithelial cells. \textit{Neoplasma}. 2009, roč.~56, č.~5, 8 s. ISSN~0028-2685.
|
