SALAJ, Peter, Petr BRABEC, Miroslav PENKA, V. POHLREICHOVÁ, Petr SMEJKAL, Petr CETKOVSKÝ, Ladislav DUŠEK and U. HEDNER. Effect of rFVIIa dose and time to treatment on patients with haemophilia and inhibitors: analysis of HemoRec registry data from the Czech Republic. Haemophilia. 2009, vol. 15, No 3, 8 pp. ISSN 1351-8216.
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Basic information
Original name Effect of rFVIIa dose and time to treatment on patients with haemophilia and inhibitors: analysis of HemoRec registry data from the Czech Republic.
Authors SALAJ, Peter (203 Czech Republic, guarantor), Petr BRABEC (203 Czech Republic), Miroslav PENKA (203 Czech Republic), V. POHLREICHOVÁ (203 Czech Republic), Petr SMEJKAL (203 Czech Republic), Petr CETKOVSKÝ (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic) and U. HEDNER (203 Czech Republic).
Edition Haemophilia, 2009, 1351-8216.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.505
RIV identification code RIV/00216224:14110/09:00039183
Organization unit Faculty of Medicine
UT WoS 000265409600014
Keywords in English bleeding; dose; haemophilia; inhibitors; registry; rFVIIa
Changed by Changed by: Ing. Petr Brabec, Ph.D., učo 135291. Changed: 4/3/2010 15:31.
Abstract
Identifying haemophilia patients with inhibitors for clinical trials is difficult due to the limited number of patients available. Registries are therefore being established as an additional means of data collection. The aim of this study was to investigate the effect of different recombinant activated factor VII (rFVIIa; NovoSeven((R))) dose ranges and dosing schedules on the incidence of re-bleeding in haemophilia patients with inhibitors. In this retrospective, uncontrolled study, data on the bleeding patterns of adult haemophilia patients with high responding inhibitors were analysed.
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