Predictive motor timing performance dissociates between early diseases of the cerebellum and Parkinson's disease

BAREŠ, Martin, Ovidiu LUNGU, Ivica HUSÁROVÁ and Tomáš GESCHEIDT. Predictive motor timing performance dissociates between early diseases of the cerebellum and Parkinson's disease. The Cerebellum. United States: Springer, 2010, vol. 9, No 1, p. 124-135. ISSN 1473-4222.

Basic information

• Original name: Predictive motor timing performance dissociates between early diseases of the cerebellum and Parkinson's disease
• Name in Czech: Načasování pohybu odlišuje časná stadia onemocnění mozečku od Parkinsonovy nemoci
• Authors: BAREŠ, Martin (203 Czech Republic, guarantor), Ovidiu LUNGU (642 Romania), Ivica HUSÁROVÁ (703 Slovakia) and Tomáš GESCHEIDT (203 Czech Republic).
• Edition: The Cerebellum, United States, Springer, 2010, 1473-4222.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30000 3. Medical and Health Sciences
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• WWW: URL
• Impact factor: Impact factor: 3.288
• RIV identification code: RIV/00216224:14110/10:00043605
• Organization unit: Faculty of Medicine
• UT WoS: 000275695000016
• Keywords (in Czech): mozeček- bazální ganglia- načasování pohybu- esenciální třes
• Keywords in English: cerebellum- basal ganglia- motor timing- essential tremor
• Tags: International impact, Reviewed

Abstract

We investigated four different groups: (1) patients with early Parkinson's disease (PD) (2) patients with sporadic spinocerebellar ataxia (SCA) (3) patients with familial essential tremor (ET) and (4) matched healthy controls. We used a predictive motor-timing task that involved mediated interception of a moving target. The main results showed that PD group and arm ET subgroup did not significantly differ from the control group. SCA and head ET subjects (severe and mild cerebellar damage, respectively) were significantly worse at interception than the other two groups. The cerebellum plays an essential role in integrating incoming visual information with the motor output in a timely manner, and that ET is a heterogeneous entity that deserves increased attention from clinicians.

Abstract (in Czech)

načasování přesného pohybu je intezivně studováno a diskutovány jsou oblasti jako mozeček a bazální ganlgia. Při behaviorálním úkolu předkládáme důkazy, že mozeček hraje dominantní roli v přesném načasování pohyby (výkon pacientů s časnou Parkinsonovou nemocí versus pacienti s onemocněním mozečku). U pacientů s sesnciálním třesem se mozeček postižen rovněž, více pokud je přítomný třes hlavy.

Links

• MSM0021622404, plan (intention): Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.