TRAMP-mediated spliceosomal intron turnover

LALÁKOVÁ, Jana a Štěpánka VAŇÁČOVÁ. TRAMP-mediated spliceosomal intron turnover. In RNA Club 2009. 2009. ISSN 1214-8598.

Základní údaje

• Originální název: TRAMP-mediated spliceosomal intron turnover
• Název česky: TRAMP-mediated spliceosomal intron turnover
• Autoři: LALÁKOVÁ, Jana a Štěpánka VAŇÁČOVÁ.
• Vydání: RNA Club 2009, 2009.

Další údaje

• Originální jazyk: angličtina
• Typ výsledku: Konferenční abstrakt
• Obor: Genetika a molekulární biologie
• Stát vydavatele: Česká republika
• Utajení: není předmětem státního či obchodního tajemství
• WWW: URL
• Organizační jednotka: Přírodovědecká fakulta
• ISSN: 1214-8598
• Klíčová slova česky: RNA Club
• Klíčová slova anglicky: RNA Club
• Příznaky: Mezinárodní význam

Anotace

In higher eukaryotes, most protein-encoding genes contain intronic sequences that need to be removed from the precursor messenger RNAs (pre-mRNAs). The intron splicing occurs in two main catalytic steps, in which introns are removed from primary transcripts in lariat forms. This process is performed by the spliceosome that is composed of five small nuclear ribonucleoprotein particles (snRNPs) and non-snRNP protein factors that bind to the pre-mRNA. The mechanism of intron removal has been described to a great detail, however, little is known about the intron degradation

Anotace česky

In higher eukaryotes, most protein-encoding genes contain intronic sequences that need to be removed from the precursor messenger RNAs (pre-mRNAs). The intron splicing occurs in two main catalytic steps, in which introns are removed from primary transcripts in lariat forms. This process is performed by the spliceosome that is composed of five small nuclear ribonucleoprotein particles (snRNPs) and non-snRNP protein factors that bind to the pre-mRNA. The mechanism of intron removal has been described to a great detail, however, little is known about the intron degradation